Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 547
interventional 386
Observational 148
Registry 13

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 161
Drug|placebo 79
Procedure 49
Device 30
Other 22
Behavioral 7
Dietary Supplement 6
Drug|Procedure 6
Device|Procedure 5
Device|Drug 3
Device|Other 3
Device|placebo 3
Diagnostic Test 2
Drug|Other 2
Other|Procedure 2
Behavioral|Drug 1
Behavioral|Drug|placebo 1
Device|Drug|Other 1
Device|Other|Procedure 1
Drug|Other|Procedure 1
Genetic 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 119
NA 37
Korea, Republic of 25
Japan 18
Belgium 13
China 12
France 11
United Kingdom 10
Austria 7
Italy 7
Taiwan 7
Brazil 6
Canada 6
Germany 5
Sweden 5
United States|Canada 5
Russian Federation 4
Switzerland 4
Turkey 4
Australia 3
Hong Kong 3
Mexico 3
Netherlands 3
Thailand 3
Colombia 2
Czechia 2
Israel 2
Malaysia 2
Norway 2
Singapore 2
United States|Australia|Belgium|Canada|France|Germany|Italy|Netherlands|Poland|South Africa|Switzerland 2
United States|Belgium|Brazil|Hungary|Italy|Mexico|Poland|Portugal 2
United States|Netherlands 2
Argentina|Australia|Austria|Belgium|Brazil|Canada|France|Germany|Hong Kong|India|Italy|Korea, Republic of|Malaysia|Mexico|Poland|Portugal|Singapore|South Africa|Spain|Switzerland|Taiwan|United Kingdom 1
Australia|Austria|Germany|Hungary 1
Australia|Bulgaria|Canada|Germany|Greece|Hong Kong|Hungary|Italy|South Africa|Spain|United Kingdom 1
Australia|Germany|United Kingdom 1
Austria|Belgium|Denmark|Finland|France|Germany|Iceland|Italy|Netherlands|Norway|Sweden|United Kingdom 1
Austria|Belgium|France|Germany 1
Austria|France|Germany|South Africa|Spain 1
Austria|Germany|Hungary|Poland 1
Belgium|Bulgaria|Czechia|Estonia|Poland|United Kingdom 1
Belgium|France 1
Belgium|France|Germany|Switzerland 1
Belgium|France|Sweden 1
Belgium|Netherlands 1
Brazil|Germany|Poland|South Africa 1
Canada|Denmark|Germany|Netherlands|Norway|Sweden 1
Chile 1
Chile|Argentina|Colombia|Venezuela 1
China|Korea, Republic of 1
Czech Republic 1
Denmark 1
Germany|Australia|Belgium|France|Hungary|Netherlands|Norway|Romania 1
Germany|Canada|Denmark|Norway|Sweden|United Kingdom 1
Greece 1
Hong Kong|Korea, Republic of|Taiwan 1
India 1
Indonesia 1
Iran, Islamic Republic of 1
Philippines 1
Poland 1
Puerto Rico 1
Romania 1
Spain 1
United States|Argentina|Australia|Bulgaria|Canada|Chile|Croatia|Estonia|France|Germany|Hungary|India|Latvia 1
United States|Argentina|Australia|Bulgaria|Canada|Chile|Croatia|Estonia|France|Germany|Hungary|India|Latvia|Lithuania 1
United States|Argentina|Bosnia and Herzegovina|Georgia|Germany|Italy|Serbia|Slovakia 1
United States|Australia|Belgium|Bulgaria|Denmark|Hungary|Israel|Netherlands|Poland|South Africa 1
United States|Australia|Belgium|France|Germany|Italy|Poland|Switzerland 1
United States|Austria|Germany|India|Italy 1
United States|Belgium|Brazil|Poland|United Kingdom 1
United States|Belgium|France|Italy 1
United States|Canada|France|Italy 1
United States|Czech Republic|Germany|Latvia|Poland|Romania 1
United States|France|Germany|Netherlands|Switzerland 1
United States|France|Germany|Poland 1
United States|Germany|Poland|United Kingdom 1
United States|Poland 1
United States|Puerto Rico 1
United States|United Kingdom 1

Sites per Study

Site_count Study_Count
1 251
2 18
3 9
4 7
5 4
6 3
7 3
8 2
9 4
10 5
11 2
12 1
13 3
14 3
15 2
17 2
19 2
20 1
21 1
23 1
24 1
25 5
26 2
30 2
31 1
35 2
36 1
38 3
39 2
40 3
41 1
42 1
43 2
44 1
45 3
51 1
52 2
54 1
59 1
60 1
61 2
62 1
63 1
64 1
65 1
71 2
79 2
83 1
84 2
85 1
88 2
93 1
95 1
96 1
98 1
99 1
102 1
103 1
153 1
181 1
186 1

Phase

Phase Study_Count
N/A 144
Phase 3 95
Phase 4 68
Phase 2 34
Phase 1 30
Phase 2/Phase 3 8
Phase 1/Phase 2 5
Early Phase 1 2

Number of Arms

Number_of_Arms Count_of_Studies
1 88
2 176
3 36
4 13
5 10
6 1
NA 62

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 8 2.00000 8.00000 4 5.0000 24.00 14.0000 2.000
1st Qu. 66 30.00000 24.25000 12 54.2500 36.00 72.5000 51.000
Median 124 60.00000 33.00000 31 115.5000 97.50 217.0000 100.000
Mean 124 99.56115 41.73333 59 187.9375 167.00 352.0421 250.806
3rd Qu. 182 120.50000 40.75000 44 247.0000 261.25 545.0000 286.000
Max. 240 907.00000 250.00000 204 832.0000 480.00 2000.0000 3029.000

Trial Group Type

group_type Group_Count
Experimental 347
Active Comparator 172
Placebo Comparator 77
NA 62
Other 40
No Intervention 11
Sham Comparator 9

Intervention Model

intervention_model Study_Count
Parallel Assignment 211
Single Group Assignment 110
Crossover Assignment 54
NA 6
Factorial Assignment 5

Primary Purpose

primary_purpose Study_Count
Treatment 282
Diagnostic 44
Basic Science 18
NA 13
Other 11
Prevention 9
Health Services Research 5
Screening 3
Supportive Care 1

Observational Studies

Studies by Country

Country Study_Count
United States 47
NA 12
Italy 9
China 8
United Kingdom 8
Germany 5
Japan 5
Korea, Republic of 5
France 4
Brazil 3
Switzerland 3
Taiwan 3
Austria 2
Belgium 2
Bulgaria 2
Canada 2
Ecuador 2
Greece 2
Thailand 2
United States|Canada 2
Australia 1
Austria|Italy|Norway|Spain|Sweden 1
Belgium|Canada|France|Luxembourg 1
Bosnia and Herzegovina 1
Chile 1
Colombia 1
Croatia 1
Czechia 1
Denmark 1
Egypt 1
Hong Kong 1
Malaysia 1
Netherlands 1
Philippines 1
Romania 1
Russian Federation 1
Saudi Arabia 1
Serbia 1
Sweden 1
Vietnam 1

Sites per Study

Site_count Study_Count
1 107
2 6
3 1
4 2
7 3
8 1
9 1
10 2
12 1
15 1
18 1
19 3
20 1
21 1
23 1
25 1
32 1
46 1
47 2
53 1
54 1
66 1
112 1
201 1
259 1
447 1
717 1
1060 1
1153 1
1638 1

Enrollment Metrics

Measure Observational
Min 7.00
1st Qu 65.00
Median 187.50
Mean 30343.34
3rd Qu 1000.00
Max 4238504.00

Observation Model

observational_model Study_Count
Cohort 76
Case-Only 25
NA 16
Case Control 13
Case-Control 9
Other 8
Case-Crossover 1

Time Perspective

time_perspective Study_Count
Prospective 103
Cross-Sectional 22
Retrospective 20
NA 3

Registries

Studies by Country

Country Study_Count
United States 7
Austria 1
Azerbaijan 1
Canada|Iran, Islamic Republic of|Japan 1
Denmark 1
Egypt 1
Korea, Republic of 1

Sites per Study

Site_count Study_Count
1 10
2 1
3 1
23 1

Enrollment Metrics

Measure Registries
Min 80.00
1st Qu 500.00
Median 1000.00
Mean 16348.38
3rd Qu 5000.00
Max 100000.00

Registry Model

observational_model Study_Count
Cohort 9
Case Control 2
Case-Only 1
Other 1

Time Perspective

time_perspective Study_Count
Prospective 13

Follow-up

target_duration Study_Count
5 Years 5
10 Years 2
1 Day 1
1 Year 1
12 Months 1
2 Years 1
3 Months 1
6 Weeks 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03553563 A Study of Esomeplazole (D961H) in Japanese Paediatric Patients With Reflux Esophagitis, Gastric Ulcer or Duodenal Ulcer https://ClinicalTrials.gov/show/NCT03553563 Recruiting AstraZeneca 2023-01-04
NCT03367195 Efficacy and Safety of DLBS2411 in the Management of GERD https://ClinicalTrials.gov/show/NCT03367195 Recruiting Dexa Medica Group 2020-10-31
NCT03341585 Influence of Expiration Lente Prolongée on Gastro-oesophageal Reflux https://ClinicalTrials.gov/show/NCT03341585 Recruiting Vrije Universiteit Brussel 2021-01-01
NCT03322553 Endoscopic Full Thickness Plication (GERD-X) for the Treatment of PPI Dependent GERD: https://ClinicalTrials.gov/show/NCT03322553 Completed Asian Institute of Gastroenterology, India 2019-08-30
NCT03299985 Diaphragmatic Myofascial Release in Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT03299985 Completed Cardenal Herrera University 2018-03-15
NCT03284177 A Trial of C13-CAC Breath Test in PPI Resistant GERD Patients https://ClinicalTrials.gov/show/NCT03284177 Completed Otsuka Pharmaceutical Co., Ltd. 2018-12-04
NCT03278327 Impact of an Endoscopic Treatment of the Line Z on the Gastronomic Recurrence and the Gastro- Esophageal Reflux Disease in the Care of the Adenocarcinoma of Barrett’s Oesophagus https://ClinicalTrials.gov/show/NCT03278327 Recruiting Institut Paoli-Calmettes 2019-06-30
NCT03270722 Functional Luminal Imaging Probe (FLIP) Topography Use in Patients With Scleroderma and Trouble Swallowing https://ClinicalTrials.gov/show/NCT03270722 Recruiting Stanford University 2020-05-31
NCT03259191 Anti-reflux Mucosectomy (ARMS) is a Useful Therapy for Refractory Gastroesophageal Reflux Disease (RGERD) https://ClinicalTrials.gov/show/NCT03259191 Recruiting Zhongda Hospital 2017-11-20
NCT03258528 Effect of Right Lateral Position on Ventilated Preterm Neonates https://ClinicalTrials.gov/show/NCT03258528 Completed Ain Shams University 2016-12-14
NCT03202537 Effectiveness of Physiologic Testing in PPI Non-Responders https://ClinicalTrials.gov/show/NCT03202537 Enrolling by invitation Northwestern University 2021-10-01
NCT03184324 Study to Evaluate the Efficacy and Safety of DWP14012 in Patients With Erosive Gastroesophageal Reflux Disease (Phase 2, Therapeutic Exploratory Study) https://ClinicalTrials.gov/show/NCT03184324 Completed Daewoong Pharmaceutical Co. LTD. 2018-04-18
NCT03130543 A Trial of Thickened Feeds to Treat Gastroesophageal Reflux in Children Admitted After Choking Spell https://ClinicalTrials.gov/show/NCT03130543 Recruiting Boston Children’s Hospital 2022-03-06
NCT03128736 Comparing Clinical Efficacy of One-Week Dual Delayed-Release Dexlansoprazole and Esomeprazole for GERD Grade A and B https://ClinicalTrials.gov/show/NCT03128736 Completed Kaohsiung Medical University Chung-Ho Memorial Hospital 2016-02-28
NCT03116841 Vonoprazan Study of Investigating the Effect on Sleep Disturbance Associated With Reflux Esophagitis- Exploratory Evaluation https://ClinicalTrials.gov/show/NCT03116841 Completed Takeda 2017-12-20
NCT03097887 Omega Loop Gastric Bypass With And Without Anti-Reflux Sutures https://ClinicalTrials.gov/show/NCT03097887 Recruiting Medical University of Vienna 2020-07-01
NCT03086070 Omeprazole 20 mg in Patients With Laryngopharyngeal reflux and Comorbid Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT03086070 Completed Children’s Hospital Srebrnjak 2010-04-30
NCT03069963 PH Metry Study to Compare the Antacid Activity of Z0063 Versus Gaviscon Double Action Tablets, in Healthy Adult Subjects https://ClinicalTrials.gov/show/NCT03069963 Completed Sanofi 2017-04-23
NCT03065816 Scintigraphy Study to Compare the Antireflux Activity of the Z0063 Versus Gaviscon Double Action Tablets, in Healthy Adult Subjects https://ClinicalTrials.gov/show/NCT03065816 Completed Sanofi 2017-05-02
NCT03041649 Mic-Key Versus Mini One Family Preference Comparison https://ClinicalTrials.gov/show/NCT03041649 Active, not recruiting Children’s Mercy Hospital Kansas City 2024-11-30
NCT03037606 Comparison of the Effect of Rabeprazole 50 mg DDR Capsules and 20 mg Enteric-coated Tablets https://ClinicalTrials.gov/show/NCT03037606 Completed Neutec Ar-Ge San ve Tic A.Åž 2018-12-01
NCT03031288 Effects of Vented Base Feeding Bottle in Preterm Infants With GERD Symptoms. https://ClinicalTrials.gov/show/NCT03031288 Completed University of Turin, Italy 2018-12-01
NCT03015610 Genotype-tailored Treatment of Symptomatic Acid-Reflux in Children With Uncontrolled Asthma https://ClinicalTrials.gov/show/NCT03015610 Recruiting Duke University 2020-08-31
NCT02987673 MGB/OAGB and LSG Effects on Lower Esophageal Sphincter (LES) Function https://ClinicalTrials.gov/show/NCT02987673 Recruiting Federico II University 2019-12-31
NCT02972047 Understanding the Pathophysiology and Effects of Diaphragmatic Breathing in Upright Gastroesophageal Reflux https://ClinicalTrials.gov/show/NCT02972047 Recruiting Mayo Clinic 2020-09-30
NCT02958046 The Efficacy of Lansoprazole and Domperidone Combination on Intragastric and Intraesophageal Acidity https://ClinicalTrials.gov/show/NCT02958046 Completed Neutec Ar-Ge San ve Tic A.Åž 2015-05-31
NCT02930824 Genotype-supported Versus Conventional Proton Pump Inhibitor Dosing https://ClinicalTrials.gov/show/NCT02930824 Completed University of Florida 2019-07-17
NCT02907632 Methoclopramide for Gastroesophageal Reflux in Premature Infants https://ClinicalTrials.gov/show/NCT02907632 Recruiting Kangaroo Foundation 2019-01-31
NCT02893709 Factors Influencing the Human Gut Microbiome Profile in Multi-ethnic Groups of the Singapore Community (FAMES) https://ClinicalTrials.gov/show/NCT02893709 Completed Changi General Hospital 2016-07-31
NCT02892357 Efficacy of Traditional Chinese Medicine Combined With Omeprazole in Patients With Non-erosive Reflux Disease https://ClinicalTrials.gov/show/NCT02892357 Recruiting Xiyuan Hospital of China Academy of Chinese Medical Sciences 2019-09-30
NCT02890979 Swallowable Sponge Cell Sampling Device and Next Generation Sequencing in Detecting Esophageal Cancer in Patients With Low or High Grade Dysplasia, Barrett Esophagus, or Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT02890979 Active, not recruiting OHSU Knight Cancer Institute 2020-12-31
NCT02873689 Efficacy and Safety of Dexlansoprazole on Heartburn Relief in Chinese Patients https://ClinicalTrials.gov/show/NCT02873689 Completed Takeda 2018-03-14
NCT02860624 Ilaprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Chinese Patients https://ClinicalTrials.gov/show/NCT02860624 Completed Livzon Pharmaceutical Group Inc. 2013-04-30
NCT02794844 Implementation of PPI Medication PGX Testing https://ClinicalTrials.gov/show/NCT02794844 Completed Nemours Children’s Clinic 2017-01-23
NCT02788591 Confocal Endomicroscopy for Non-Erosive Reflux Disease Detection https://ClinicalTrials.gov/show/NCT02788591 Recruiting LCMC Health 2020-12-31
NCT02786810 Contrast Enhanced Ultrasound for Evaluation of Reflux Nephropathy https://ClinicalTrials.gov/show/NCT02786810 Completed University of Tennessee 2016-11-30
NCT02783378 48 Hours Esophagal pH-monitoring With and Without Gaviscon https://ClinicalTrials.gov/show/NCT02783378 Completed Universitair Ziekenhuis Brussel 2017-08-01
NCT02776982 Influence of Central Obesity on the Esophageal Epithelial Barrier https://ClinicalTrials.gov/show/NCT02776982 Active, not recruiting Mayo Clinic 2020-06-30
NCT02755753 A Study to Evaluate REbamiPide as an Adjuvant Regimen to Heal erosIve Reflux Esophagitis https://ClinicalTrials.gov/show/NCT02755753 Completed Severance Hospital 2016-01-31
NCT02743949 Comparison of Vonoprazan to Esomeprazole in Participants With Symptomatic GERD Who Responded Partially to a High Dose of Proton Pump Inhibitor (PPI) https://ClinicalTrials.gov/show/NCT02743949 Completed Takeda 2018-10-05
NCT02710955 SWAN: Study on the Tolerance and Efficacy of a New Anti-regurgitation Formula (PC-2016-01) https://ClinicalTrials.gov/show/NCT02710955 Completed United Pharmaceuticals 2017-01-21
NCT02706938 Impact of Head of Bed Elevation in Symptoms of Patients With Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT02706938 Completed Universidad Nacional de Colombia 2017-11-15
NCT02689999 The Effect of Dexrabeprazole on Intragastric and Intraesophageal Acidity https://ClinicalTrials.gov/show/NCT02689999 Completed Neutec Ar-Ge San ve Tic A.Åž 2017-05-31
NCT02685436 Role of Pepsin Assay in Wheezy Infants https://ClinicalTrials.gov/show/NCT02685436 Completed Mansoura University Children Hospital 2015-05-31
NCT02685150 Endoscopic Tri-Modal Imaging to Distinguish Functional Dyspepsia From Reflux Disease https://ClinicalTrials.gov/show/NCT02685150 Completed Chinese PLA General Hospital 2018-06-30
NCT02670642 Open, Randomised, Multi-center Study of on Demand Versus Continuous Esomeprazole Treatment in Patient With GERD https://ClinicalTrials.gov/show/NCT02670642 Completed AstraZeneca 2002-11-30
NCT02637557 A Trial of IW-3718 for 8 Weeks in Patients With Symptomatic Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT02637557 Completed Ironwood Pharmaceuticals, Inc. 2017-04-26
NCT02623062 Compound Sodium Alginate Oral Suspension Sachet Symptomatic Relief Study https://ClinicalTrials.gov/show/NCT02623062 Completed Reckitt Benckiser Healthcare (UK) Limited 2016-03-31
NCT02620241 Influence of Intrapulmonary Percussive Ventilation (IPV) on Gastro-oesophageal Reflux (GOR). https://ClinicalTrials.gov/show/NCT02620241 Completed Vrije Universiteit Brussel 2017-10-31
NCT02592902 Recurrent Respiratory Papillomatosis and Extraesophageal Reflux https://ClinicalTrials.gov/show/NCT02592902 Completed University Hospital Ostrava 2018-08-31
NCT02558049 Should I Continue Taking My Acid Reflux Medication? Development and Pilot Testing of a Patient Decision Aid https://ClinicalTrials.gov/show/NCT02558049 Completed University of Ottawa 2016-12-31
NCT02556021 Study to Evaluate the Safety and Efficacy of CJ-12420 in Patients With Non Erosive Reflux Disease https://ClinicalTrials.gov/show/NCT02556021 Completed CJ HealthCare Corporation 2016-11-01
NCT02530216 Evaluating the Impact of Automated Evaluation of Gastrointestinal Symptoms (AEGIS) on Clinical Outcomes https://ClinicalTrials.gov/show/NCT02530216 Completed Cedars-Sinai Medical Center 2018-02-07
NCT02505945 The CALIBER Study Randomized Controlled Trial of LINX Versus Double-Dose Proton Pump Inhibitor Therapy for Reflux Disease https://ClinicalTrials.gov/show/NCT02505945 Completed Torax Medical Incorporated 2017-10-31
NCT02486263 Neonatal Gastro-Esophageal Reflux Disease (GERD) Management Trial https://ClinicalTrials.gov/show/NCT02486263 Active, not recruiting Nationwide Children’s Hospital 2020-03-31
NCT02457429 A Validation Study of the Dx-pH Probe in Children for the Detection of Extra-oesophageal Reflux https://ClinicalTrials.gov/show/NCT02457429 Completed Manchester University NHS Foundation Trust 2017-04-28
NCT02445014 Pilot Study to Image the Esophagus Using a SECM Tethered Endoscopic Capsule https://ClinicalTrials.gov/show/NCT02445014 Completed Massachusetts General Hospital 2016-01-31
NCT02436057 Development and Validation of the Automated Evaluation of Gastrointestinal Symptoms (AEGIS) Platform https://ClinicalTrials.gov/show/NCT02436057 Completed Cedars-Sinai Medical Center 2015-12-31
NCT02429830 A Study of Reflux Management With the LINX® System for Gastroesophageal Reflux Disease After Laparoscopic Sleeve Gastrectomy https://ClinicalTrials.gov/show/NCT02429830 Active, not recruiting Torax Medical Incorporated 2021-12-31
NCT02425423 Study on the Tolerance and Efficacy of a New Anti Regurgitation Formula https://ClinicalTrials.gov/show/NCT02425423 Completed United Pharmaceuticals 2014-03-31
NCT02401035 PREA, PK And Safety PASS Study Of IV Pantoprazole In Pediatric Subjects https://ClinicalTrials.gov/show/NCT02401035 Recruiting Pfizer 2022-04-11
NCT02384551 Dietary Carbohydrate and GERD in Veterans https://ClinicalTrials.gov/show/NCT02384551 Recruiting VA Office of Research and Development 2020-09-30
NCT02359604 The Gastrointestinal Microbiome of Infants With GERD and PPI Therapy: a Pilot Study https://ClinicalTrials.gov/show/NCT02359604 Completed Medical University of Graz 2017-02-07
NCT02351960 Dexlansoprazole in Asian Participants With Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT02351960 Completed Takeda 2016-06-22
NCT02336100 Diagnostic Value of Flexible Spectral Imaging Color Enhancement (FICE) Plus Probe-based Confocal Laser Endomicroscopy (pCLE) for Minimal Change Esophageal Reflux Disease (MERD) Diagnosis https://ClinicalTrials.gov/show/NCT02336100 Completed King Chulalongkorn Memorial Hospital 2012-02-29
NCT02318862 Assessment of Esophageal Epithelium Integrity With Mucosal Impedance https://ClinicalTrials.gov/show/NCT02318862 Completed Vanderbilt University Medical Center 2016-12-31
NCT02288988 Minimally Invasive Collis-Nissen for the Treatment of Short Esophagus https://ClinicalTrials.gov/show/NCT02288988 Completed University of Bologna 2013-12-31
NCT02226484 Can Quercetin Increase Claudin-4 and Improve Esophageal Barrier Function in GERD? https://ClinicalTrials.gov/show/NCT02226484 Completed University of North Carolina, Chapel Hill 2016-05-31
NCT02200055 Using Electrical Bioimpedance Assessments to Estimate Perioperative Total Body Water and Postoperative Fluid Need https://ClinicalTrials.gov/show/NCT02200055 Completed United States Naval Medical Center, Portsmouth 2015-07-31
NCT02186652 PK Study With Pantoprazole in Obese Children and Adolescents https://ClinicalTrials.gov/show/NCT02186652 Completed Duke University 2015-09-13
NCT02154659 The Difference of Reflux Pattern Between the Patients Who Have Postprandial Reflux Symptoms https://ClinicalTrials.gov/show/NCT02154659 Completed Yonsei University 2015-12-07
NCT02153398 A Phase I/III Study of D961H 10 mg and 20 mg in Japanese Paediatric Patients With Gastrointestinal Acid Related Diseases https://ClinicalTrials.gov/show/NCT02153398 Completed AstraZeneca 2016-04-30
NCT02141711 TAK-438 - Safety, Blood Levels & Effects of Repeated Doses https://ClinicalTrials.gov/show/NCT02141711 Completed Takeda 2009-02-28
NCT02135107 A Double-blind Comparative Study of the Efficacy and Safety of E3810 10mg Once and Twice Daily in Maintenance Therapy for PPI Resistant Gastroesophageal Reflux Disease Patients https://ClinicalTrials.gov/show/NCT02135107 Completed Eisai Inc. 2016-05-31
NCT02128867 Safety Study of Airway Clearance Techniques in Infants. https://ClinicalTrials.gov/show/NCT02128867 Completed Vrije Universiteit Brussel 2015-01-31
NCT02124863 Influence of IPV on GOR in Infants From 0 to 12 Months. https://ClinicalTrials.gov/show/NCT02124863 Completed Vrije Universiteit Brussel 2015-01-31
NCT02114216 Nociceptors, Neurotrophic Factors and Cytokine Expression in Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT02114216 Completed Seoul National University Bundang Hospital 2014-08-31
NCT02100189 Esophageal Cytology With FISH in Detecting Esophageal Cancer https://ClinicalTrials.gov/show/NCT02100189 Completed OHSU Knight Cancer Institute 2015-12-31
NCT02096458 Sensory Evaluation of Dexlansoprazole Delayed-Release Orally Disintegrating Tablets https://ClinicalTrials.gov/show/NCT02096458 Completed Takeda 2014-02-28
NCT02081404 Diagnosis of Acid Reflux Disease Using Novel Imaging: A Prospective Study https://ClinicalTrials.gov/show/NCT02081404 Recruiting Midwest Biomedical Research Foundation 2020-03-31
NCT02072447 Absolute Bioavailability of YH4808 With Accelerator Mass Spectrometry(AMS)-Based Microdose Study https://ClinicalTrials.gov/show/NCT02072447 Completed Seoul National University Hospital 2014-04-30
NCT02060500 Cardiaplication: A Novel Antireflux Operation https://ClinicalTrials.gov/show/NCT02060500 Completed Emory University 2015-02-28
NCT01307982 Comparative Anti-Reflux Procedures in Neurologically Impaired Children https://ClinicalTrials.gov/show/NCT01307982 Completed University of Utah 2013-09-30
NCT01288612 Comparative Effectiveness of Endoscopic Assessment of Gastroesophageal Reflux and Barretts Esophagus https://ClinicalTrials.gov/show/NCT01288612 Completed Mayo Clinic 2013-10-31
NCT01269788 Comparing Omeprazole With Fluoxetine for Treatment of Non Erosive Reflux Disease and Its Subgroups: a Double-blind Placebo-controlled Clinical Trial https://ClinicalTrials.gov/show/NCT01269788 Completed Tehran University of Medical Sciences 2011-08-31
NCT02030925 Ph2a Study to Evaluate IW-3718 in Patients With Gastroesophageal Reflux Not Completely Responsive to Proton Pump Inhibitors https://ClinicalTrials.gov/show/NCT02030925 Completed Ironwood Pharmaceuticals, Inc. 2014-12-31
NCT04454112 Pre and Post-gastrostomy Evaluation of GER in Children Using 24-hour pH Monitoring https://ClinicalTrials.gov/show/NCT04454112 Completed Ondokuz Mayıs University 2018-12-12
NCT03346174 Influence of Airway Clearance Techniques on GOR in Infants https://ClinicalTrials.gov/show/NCT03346174 Recruiting Vrije Universiteit Brussel 2021-01-01
NCT01946971 Lansoprazole in Preterm Infants With Gastroesophageal Reflux (GER) https://ClinicalTrials.gov/show/NCT01946971 Completed Seoul National University Hospital 2014-07-31
NCT01915173 Response to Supplement and Placebo in GERD https://ClinicalTrials.gov/show/NCT01915173 Completed Beth Israel Deaconess Medical Center 2014-04-30
NCT01888549 Efficacy of Proton Pump Inhibitor for Chronic Cough Caused by Gastroesophageal Reflux; Double-blind, Placebo-controlled, Randomized Clinical Trial https://ClinicalTrials.gov/show/NCT01888549 Completed Yonsei University 2016-02-29
NCT01882088 Phase IV Study of the Impact of Dietary Fibers on Symptoms and Esophageal Motility in Patients With Non-erosive GERD https://ClinicalTrials.gov/show/NCT01882088 Completed Russian Academy of Medical Sciences 2016-09-30
NCT01880892 Laryngopharyngeal Reflux Before and After Cricopharyngeal Myotomy https://ClinicalTrials.gov/show/NCT01880892 Recruiting Mayo Clinic 2022-04-30
NCT01878526 Gastroesophageal Reflux Treatment in Scleroderma https://ClinicalTrials.gov/show/NCT01878526 Completed Khon Kaen University 2015-08-31
NCT01872897 Compound Sodium Alginate Double Action Chewable Tablets 4-hour Esophageal pH Study in GERD Patients https://ClinicalTrials.gov/show/NCT01872897 Completed Reckitt Benckiser Healthcare (UK) Limited 2013-12-31
NCT01869491 Compound Sodium Alginate Double Action Chewable Tablet Symptomatic Relief Study https://ClinicalTrials.gov/show/NCT01869491 Completed Reckitt Benckiser Healthcare (UK) Limited 2014-05-31
NCT01857713 Treatment of Extraesophageal Reflux With the Reza Band UES Assist Device https://ClinicalTrials.gov/show/NCT01857713 Completed Somna Therapeutics, L.L.C. 2013-09-30
NCT01854970 Benefit of Pharyngeal and Oesophageal pH-impedance of Patients With High Suspicion of Laryngopharyngeal Reflux https://ClinicalTrials.gov/show/NCT01854970 Completed University Hospital, Bordeaux 2015-07-31
NCT01844440 Diagnostic of Transient Lower Esophageal Sphincter Relaxation With Combined Impedance and High Resolution Manometry in Patients With GERD https://ClinicalTrials.gov/show/NCT01844440 Completed University Hospital, Bordeaux 2014-01-31
NCT01819454 The Diagnostics of Extraesophageal Reflux With the Restech System https://ClinicalTrials.gov/show/NCT01819454 Completed University Hospital Ostrava 2015-09-30
NCT01818570 A Study of Local Effect and Safety of a Single PPC-5650 Dose on Reflux Pain During Pain Stimulation in the Esophagus https://ClinicalTrials.gov/show/NCT01818570 Completed Aalborg University Hospital 2014-01-31
NCT01806220 Laryngeal and Esophageal EGF-r Expression in Patients With Reflux Laryngitis https://ClinicalTrials.gov/show/NCT01806220 Completed Faculdade de Ciências Médicas da Santa Casa de São Paulo 2007-12-31
NCT01798212 Prospective Trial on the Clinical Feasibility of a New Full Thickness Endoscopic Plication Device for Patients With GERD. https://ClinicalTrials.gov/show/NCT01798212 Completed Krankenhaus Barmherzige Schwestern Linz 2016-12-31
NCT01778101 Lansoprazole in Preterm Infants With Reflux https://ClinicalTrials.gov/show/NCT01778101 Completed Seoul National University Hospital 2013-05-31
NCT01753128 Efficacy of Imipramine for Treatment of Patients With Esophageal Hypersensitivity/ Functional Heartburn https://ClinicalTrials.gov/show/NCT01753128 Completed Mahidol University 2013-09-30
NCT01750437 Phase 2 Clinical Trial to Investigate the Safety, Tolerability and Efficacy of YH1885L in Patients With Non-erosive Reflux Disease(NERD) https://ClinicalTrials.gov/show/NCT01750437 Completed Yuhan Corporation 2013-10-31
NCT01733810 The Role of HIF-2a in the Pathogenesis of Reflux Esophagitis https://ClinicalTrials.gov/show/NCT01733810 Completed Dallas VA Medical Center 2015-07-31
NCT01710995 A Three-Period Study to Investigate the Relative Bioavailability and Pharmacodynamic Profiles of a Zegerid 20mg Capsule, Zegerid 20mg Powder for Oral Suspension and Losec 20mg Capsule in Healthy Adult Volunteers Under Fasting Conditions https://ClinicalTrials.gov/show/NCT01710995 Completed Norgine 2010-11-30
NCT01696734 Domperidone in Treating Patients With Gastrointestinal Disorders https://ClinicalTrials.gov/show/NCT01696734 Recruiting M.D. Anderson Cancer Center 2021-10-31
NCT01682265 Stretta In Reflux Uncontrolled by IPP https://ClinicalTrials.gov/show/NCT01682265 Completed Nantes University Hospital 2018-11-27
NCT01669811 Compare D961H 20 mg Bid and 20 mg qd in Patients With Refractory Reflux Esophagitis (Inflammation of Lower Esophagus) https://ClinicalTrials.gov/show/NCT01669811 Completed AstraZeneca 2014-05-31
NCT01669330 Laparoscopic Nissen Versus Anterior Partial Fundoplication https://ClinicalTrials.gov/show/NCT01669330 Completed Region Skane 2013-12-31
NCT01657578 Optimal Dosing of Omeprazole in Neonates https://ClinicalTrials.gov/show/NCT01657578 Completed Assistance Publique - Hôpitaux de Paris 2010-12-31
NCT01642615 Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules for Healing of Erosive Esophagitis and Maintenance of Healed Erosive Esophagitis and Relief of Heartburn in Adolescents https://ClinicalTrials.gov/show/NCT01642615 Completed Takeda 2014-11-30
NCT01642602 Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules in Treating Symptomatic Non-Erosive Gastroesophageal Reflux Disease in Adolescents https://ClinicalTrials.gov/show/NCT01642602 Completed Takeda 2014-01-31
NCT01578642 Feasibility Study for Evaluating the Effect of Electrical Stimulation on Lower Esophageal Sphincter Pressure and Esophageal Acid Exposure in Patients With Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT01578642 Completed EndoStim Inc. 2013-05-31
NCT01538849 Study to Investigate the Safety, Tolerability and Efficacy of YH4808 in Patients With Reflux Esophagitis https://ClinicalTrials.gov/show/NCT01538849 Completed Yuhan Corporation 2013-11-30
NCT01503476 Development of Applications of the Bravo® pH Monitoring System and Evaluation of Its Performance https://ClinicalTrials.gov/show/NCT01503476 Completed Medtronic - MITG 2016-03-31
NCT01493089 Phase III Study Comparing Zegerid® With Losec® for the Relief of Heartburn Associated With Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT01493089 Completed Norgine 2011-10-31
NCT01474369 Efficacy of TAK-438 Compared to Placebo in the Treatment of Non-Erosive Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT01474369 Completed Takeda 2013-02-28
NCT01472939 Selective 5-HT4 Receptor Agonist and Proton Pump Inhibitor (PPI) in Subjects With Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT01472939 Completed Shire 2013-05-31
NCT01450748 Efficacy and Safety of Alginos Oral Suspension to Treat Laryngopharyngeal Reflux https://ClinicalTrials.gov/show/NCT01450748 Completed TTY Biopharm 2015-03-31
NCT01400945 Efficacy Study of AGSPT201 Tablet to Treat Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT01400945 Completed Ahn-Gook Pharmaceuticals Co.,Ltd 2011-08-31
NCT01397084 To Assess the Efficacy of Esomeprazole 20mg Once Daily in Subjects Who Still Had Heartburn After Receiving Rabeprazole https://ClinicalTrials.gov/show/NCT01397084 Completed AstraZeneca 2012-01-31
NCT01390714 Pharmacodynamic and Pharmacokinetic Study of E3710 Following Oral Administration to Healthy, Male, Japanese Subjects https://ClinicalTrials.gov/show/NCT01390714 Completed Eisai Inc. 2011-10-31
NCT01381991 The Efficacy of i-Scan for Detecting Reflux Esophagitis https://ClinicalTrials.gov/show/NCT01381991 Completed Konkuk University Hospital 2010-11-30
NCT01364610 An Assessment of pH Testing Methods https://ClinicalTrials.gov/show/NCT01364610 Completed University of Calgary 2008-12-31
NCT01349413 BRAVO Study for Functional Dyspepsia https://ClinicalTrials.gov/show/NCT01349413 Completed Chinese University of Hong Kong 2017-12-30
NCT01338077 Efficacy and Safety of Sodium Alginate Oral Suspension to Treat Non-erosive Gastro-esophageal Reflux Disease https://ClinicalTrials.gov/show/NCT01338077 Completed Chang Gung Memorial Hospital 2012-01-31
NCT01324986 A Study on the Effectiveness of Laparoscopic Fundoplication on Extraesophageal Manifestations of Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT01324986 Completed General Public Hospital Zell am See NA
NCT01324791 Laparoscopic Antireflux Surgery Versus Endoscopic Full-thickness Gastroplication for Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT01324791 Completed General Public Hospital Zell am See NA
NCT01321294 Laparoscopic Nissen Versus Toupet Fundoplication: Objective and Subjective Results of a Prospective Randomized Trial https://ClinicalTrials.gov/show/NCT01321294 Completed General Public Hospital Zell am See NA
NCT04436159 Partial Versus Total Fundoplication in the Surgical Repair of Para-esophageal Hernia. https://ClinicalTrials.gov/show/NCT04436159 Recruiting Karolinska University Hospital 2020-09-30
NCT04410211 Comparison Between Two Types of Sedation for Elective Upper Endoscopy Procedures https://ClinicalTrials.gov/show/NCT04410211 Completed University of Malaya 2019-11-30
NCT04355455 Effects of Serotonin Agonist Citalopram on Multimodal Esophageal Stimulation in Healthy Volunteers https://ClinicalTrials.gov/show/NCT04355455 Completed Universitaire Ziekenhuizen Leuven 2011-12-31
NCT04352686 Effects of Serotonin Agonist Buspirone on Multimodal Esophageal Stimulation in Healthy Volunteers https://ClinicalTrials.gov/show/NCT04352686 Completed Universitaire Ziekenhuizen Leuven 2012-09-30
NCT04335734 Influence of Wrap Fixation Technique on the Results of Fundoplication https://ClinicalTrials.gov/show/NCT04335734 Completed Odessa National Medical University 2014-10-01
NCT04325620 Safety to Evaluate the Efficacy and Safety of HIP1601 in Patients With Non Erosive Reflux Disease https://ClinicalTrials.gov/show/NCT04325620 Recruiting Hanmi Pharmaceutical Company Limited 2020-07-16
NCT04292470 Physiology of GERD and Treatment Response https://ClinicalTrials.gov/show/NCT04292470 Recruiting University of California, Davis 2021-11-30
NCT04287972 A Study to Reduce the Reflux After a Sleeve Gastrectomy in Obese Patients https://ClinicalTrials.gov/show/NCT04287972 Recruiting Ente Ospedaliero Cantonale, Bellinzona 2022-10-31
NCT04282954 Clinical Trial to Evaluate the Safety and Efficacy of JP-1366 in Patients With Erosive Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT04282954 Recruiting Jeil Pharmaceutical Co., Ltd. 2020-11-30
NCT04255693 Real-life Study of Changes of Gastroesophageal Reflux Disease Manifestations Due to Behavioural and Diet Adherence https://ClinicalTrials.gov/show/NCT04255693 Recruiting Federal State Budgetary Scientific Institution "Federal Research Centre of Nutrition, Biotechnology 2023-12-31
NCT04253444 The Effect of Autonomic Modulation on Symptoms in Patients With Reflux Hypersensitivity https://ClinicalTrials.gov/show/NCT04253444 Recruiting Queen Mary University of London 2021-02-01
NCT04202692 Effect of a Combination Oral Formulation of Hyaluronic Acid, Chondroitin Sulphate and Magnesium Trisilicate in Patients With Gastro-Esophageal Reflux Disease Not Fully Satisfied With Their Treatment https://ClinicalTrials.gov/show/NCT04202692 Recruiting SOFAR S.p.A. 2020-12-31
NCT04202276 The Study of Nutrition of Children and Adolescents With GERD https://ClinicalTrials.gov/show/NCT04202276 Enrolling by invitation Federal State Budgetary Scientific Institution "Federal Research Centre of Nutrition, Biotechnology 2019-06-30
NCT04194723 Antireflux Mucosectomy (ARMS) for Treatment of Gastroesophageal Reflux https://ClinicalTrials.gov/show/NCT04194723 Recruiting Chinese University of Hong Kong 2021-12-31
NCT04152798 Approach to Hiatal Hernia Repair Based on Collagen Study https://ClinicalTrials.gov/show/NCT04152798 Completed Odessa National Medical University 2019-09-20
NCT04130659 Study to Evaluate the Performance and Safety of the Marial in Association With PPI Versus PPI Alone https://ClinicalTrials.gov/show/NCT04130659 Recruiting Nekkar Lab Srl 2019-11-30
NCT04118647 Effective Mechanisms of Wu-Chu-Yu Tang on Gastroesophageal Disorder https://ClinicalTrials.gov/show/NCT04118647 Recruiting China Medical University Hospital 2021-09-30
NCT04080726 Efficacy and Safety of HIP1601 Capsule https://ClinicalTrials.gov/show/NCT04080726 Recruiting Hanmi Pharmaceutical Company Limited 2019-11-30
NCT04065516 ARAT for Reflux Disease After Peroral Endoscopic Myotomy in Patients With Achalasia https://ClinicalTrials.gov/show/NCT04065516 Enrolling by invitation Coordinación de Investigación en Salud, Mexico 2019-11-01
NCT04036942 Antireflux Ablation Therapy (ARAT) Vs Antireflux Mucosectomy (ARMS) In The Management Of Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT04036942 Recruiting Coordinación de Investigación en Salud, Mexico 2019-11-01
NCT04028466 Effectiveness of Vonoprazan vs Omeprazole as Empiric Therapy for Gastroesophageal Reflux Disease (GERD) Patients Without Alarm Features https://ClinicalTrials.gov/show/NCT04028466 Recruiting St. Luke’s Medical Center, Philippines 2020-11-30
NCT04001400 Treatment Response of High-dose and Standard-dose Rabeprazole for Extra-esophageal Reflux. https://ClinicalTrials.gov/show/NCT04001400 Completed Seoul National University Hospital 2014-05-21
NCT03999502 Endomina Suturing Device as a Treatment of GERD. https://ClinicalTrials.gov/show/NCT03999502 Recruiting Erasme University Hospital 2020-05-12
NCT03998969 Efficacy of DA-5204 on Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT03998969 Completed Seoul National University Hospital 2018-12-11
NCT03928470 Clinical Trial to Evaluate the Efficacy and Safety of EsoDuo Tab. 20/800mg https://ClinicalTrials.gov/show/NCT03928470 Completed Chong Kun Dang Pharmaceutical 2019-12-20
NCT03904758 Extraesophageal Reflux - Feasibility of Measurement of Pepsin in Saliva as a Diagnostic Option https://ClinicalTrials.gov/show/NCT03904758 Recruiting University Hospital Ostrava 2021-11-30
NCT03904472 Cognitive Behavioral Therapy for Insomnia (CBTI) in GERD Patients With Insomnia https://ClinicalTrials.gov/show/NCT03904472 Recruiting University of Michigan 2021-04-30
NCT03883074 Effect of a Combination of Hyaluronic Acid, Chondroitin Sulphate and Magnesium Trisilicate on Subjects With GastroEsophageal Reflux Disease https://ClinicalTrials.gov/show/NCT03883074 Recruiting SOFAR S.p.A. 2020-10-31
NCT03881722 Effect of Magnesium Alginate in Infants With Gastroesophageal Reflux. https://ClinicalTrials.gov/show/NCT03881722 Completed Policlinico Hospital 2018-12-31
NCT03835442 A Placebo Controlled Trial With Baclofen for the Treatment of GERD Patients With Incomplete PPI Response https://ClinicalTrials.gov/show/NCT03835442 Completed Universitaire Ziekenhuizen Leuven 2016-12-31
NCT03811080 Study to Evaluate the Efficacy and Safety of DWP14012 in Patients With Non Erosive Reflux Disease https://ClinicalTrials.gov/show/NCT03811080 Recruiting Daewoong Pharmaceutical Co. LTD. 2020-02-29
NCT03793556 Evaluation of GERDOFF Efficacy in Combination With Proton Pump Inhibitor https://ClinicalTrials.gov/show/NCT03793556 Completed SOFAR S.p.A. 2018-09-20
NCT03788109 Relationship Between Gastric Accommodation, TLESRs and Reflux in HV and in GERD With or Without Overlapping Dyspepsia https://ClinicalTrials.gov/show/NCT03788109 Completed Universitaire Ziekenhuizen Leuven 2018-06-15
NCT03777787 Bitter Tastants and Reflux https://ClinicalTrials.gov/show/NCT03777787 Completed Universitaire Ziekenhuizen Leuven 2019-05-10
NCT03776669 Laparoscopic Sleeve Gastrectomy With or Without Hiatal Hernia Repair in Morbidly Obese Patients https://ClinicalTrials.gov/show/NCT03776669 Recruiting National Taiwan University Hospital 2020-11-01
NCT03746691 Effect of Citalopram on Reflux Episodes in Healthy Volunteers https://ClinicalTrials.gov/show/NCT03746691 Completed Universitaire Ziekenhuizen Leuven 2017-07-31
NCT03736369 Study to Evaluate the Efficacy and Safety of DWP14012 in Patients With Erosive Gastroesophageal Reflux Disease (Phase 3) https://ClinicalTrials.gov/show/NCT03736369 Completed Daewoong Pharmaceutical Co. LTD. 2019-08-07
NCT03692455 Clinico-functional Evaluation of GERD: Comparative Study of Vertical Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass https://ClinicalTrials.gov/show/NCT03692455 Completed Clinica Gastrobese 2018-08-13
NCT03676374 Prucalopride Treatment for Refractory Gastro-esophageal Reflux Disease https://ClinicalTrials.gov/show/NCT03676374 Recruiting Universitaire Ziekenhuizen Leuven 2021-04-30
NCT03659487 Comparison of Total and Partial Fundoplication During Surgery of Patients With Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT03659487 Completed Karolinska Institutet 2011-04-30
NCT03634449 Risks of Gastroesophageal Reflux in the Endotracheal Intubation or the I-gel https://ClinicalTrials.gov/show/NCT03634449 Recruiting National Taiwan University Hospital 2019-10-13
NCT03619811 Precision Approach to PPI Therapy in Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT03619811 Recruiting University of California, San Diego 2020-07-31
NCT03591653 A Multi-center, Randomized, Double-blind, Parallel-group, Placebo Controlled Phase III Study to Evaluate the Efficacy and Safety of LXI-15028 in Non-erosive Reflux Disease in Chinese Patients for 4 Weeks https://ClinicalTrials.gov/show/NCT03591653 Completed Shandong Luoxin Pharmaceutical Group Stock Co., Ltd. 2019-10-30
NCT03561883 Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors https://ClinicalTrials.gov/show/NCT03561883 Recruiting Ironwood Pharmaceuticals, Inc. 2021-06-30
NCT03561233 Prevalence and Predictors of Proton Pump Inhibitor Partial Response in Gastroesophageal Reflux Disease in Systemic Sclerosis https://ClinicalTrials.gov/show/NCT03561233 Completed Khon Kaen University 2018-05-31
NCT03548298 Antireflux Ablation Therapy (ARAT) for Gastroesophageal Reflux Treatment https://ClinicalTrials.gov/show/NCT03548298 Completed Coordinación de Investigación en Salud, Mexico 2019-07-01
NCT03516188 Efficacy of Gaviscon-Advance® in Suppressing Post-supper Acid-pocket and Night-time Acid-reflux in Obese Participants https://ClinicalTrials.gov/show/NCT03516188 Completed Universiti Sains Malaysia 2017-06-30
NCT03497494 the Related Factors of Bariatric Surgery on Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT03497494 Active, not recruiting First Affiliated Hospital of Jinan University 2019-12-30
NCT03476265 Lower Esophageal Sphincter (LES) Stimulation in Patients With Ineffective Esophageal Motility https://ClinicalTrials.gov/show/NCT03476265 Completed Austrian Society Of Surgical Oncology 2018-01-15
NCT03467438 Efficacy of Zinc L-carnosine in Maintaining Remission of Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT03467438 Recruiting IRCCS Policlinico S. Matteo 2020-04-01
NCT03444883 Phase III Study to Evaluate Safety and Efficacy of Ilaprazole in Patients With NERD https://ClinicalTrials.gov/show/NCT03444883 Completed Il-Yang Pharm. Co., Ltd. 2020-02-25
NCT03436914 Treatment Response of Maintenance Dose of Proton Pump Inhibitor in Patients With Nonerosive Gatroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT03436914 Completed Yonsei University 2019-10-18
NCT03425097 Fexofenadine Use in Gastroesophageal Reflux Symptoms https://ClinicalTrials.gov/show/NCT03425097 Recruiting Stanford University 2020-03-31
NCT03417817 Oesophageal Acid Exposure in Healthy Subjects Over 96 Hours https://ClinicalTrials.gov/show/NCT03417817 Completed Guy’s and St Thomas’ NHS Foundation Trust 2019-06-30
NCT01265550 A Randomized Trial of Medical and Surgical Treatments for Patients With GERD Symptoms That Are Refractory to Proton Pump Inhibitors https://ClinicalTrials.gov/show/NCT01265550 Completed VA Office of Research and Development 2016-12-30
NCT01260935 Comparison of Laparoscopic Hill and Laparoscopic Nissen Anti-Reflux Procedures https://ClinicalTrials.gov/show/NCT01260935 Completed Swedish Medical Center 2010-11-30
NCT01212614 Measurement of Gastric Secretion by MRI Under Inhibition by ProtonPump Inhibitors in Healthy Subjects & in GERD Patients https://ClinicalTrials.gov/show/NCT01212614 Completed University of Zurich 2012-09-30
NCT01161602 A Study to Evaluate the Safety, Tolerability and Pharmacodynamics of Pumosetrag in Patients With Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT01161602 Completed Edusa Pharmaceuticals, Inc. NA
NCT01154634 Study to Investigate the Pharmacodynamic Effect of a Single Dose of AZD2516 in Healthy Male Subjects https://ClinicalTrials.gov/show/NCT01154634 Completed AstraZeneca 2010-09-30
NCT01149395 Can E-cadherin Found in Tissue/Blood be Valuable in Identifying & Monitoring Patients With Post-proton Pump Inhibitor (PPI)-Responsive Heartburn https://ClinicalTrials.gov/show/NCT01149395 Completed University of North Carolina, Chapel Hill 2012-04-30
NCT01136980 Randomized EsophyX Versus Sham / Placebo Controlled TIF Trial: The RESPECT Study https://ClinicalTrials.gov/show/NCT01136980 Completed EndoGastric Solutions 2015-04-30
NCT01136317 Comparison of Antisecretory Effect of a Single Dose of Rabeprazole 20 mg and Omeprazole 20 mg in Obese Subjects https://ClinicalTrials.gov/show/NCT01136317 Completed Nantes University Hospital 2010-07-31
NCT01135368 Safety and Efficacy of Lansoprazole in Patients With Reflux Disease https://ClinicalTrials.gov/show/NCT01135368 Completed Takeda 2008-09-30
NCT01132638 Pantoprazole Magnesium 40 mg Versus Esomeprazole 40 mg in Patients With Erosive Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT01132638 Completed Takeda 2012-06-30
NCT01126034 Improving Metoclopramide Prescribing Practices at Penn Through a Physician-targeted Intervention https://ClinicalTrials.gov/show/NCT01126034 Completed University of Pennsylvania 2008-04-30
NCT01119768 Esomeprazole Treatment Co-diagnosed Non Erosive Reflux Disease (NERD) and Chronic Gastritis Patients https://ClinicalTrials.gov/show/NCT01119768 Completed AstraZeneca 2011-06-30
NCT01118585 Transoral Incisionless Fundoplication (TIF) Registry Study for Treatment of Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT01118585 Completed EndoGastric Solutions 2015-06-30
NCT01110811 Transoral Incisionless Fundoplication (TIF) Versus Sham for Treatment of Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT01110811 Completed EndoGastric Solutions 2015-09-30
NCT01101646 A Pharmacokinetic and Relative Bioavailability Study With Rabeprazole Sodium in Healthy Adult Volunteers https://ClinicalTrials.gov/show/NCT01101646 Completed Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 2008-09-30
NCT01095133 Do Acid Sensing Ion Channels Contribute to Heartburn? https://ClinicalTrials.gov/show/NCT01095133 Completed University of North Carolina, Chapel Hill 2011-09-30
NCT01079884 Gastroesophageal Reflux Disease (GERD)/Nighttime Heartburn and Driving Performance https://ClinicalTrials.gov/show/NCT01079884 Completed Digestive & Liver Disease Specialists 2011-03-31
NCT01065649 Effect of Nortriptyline in Cortical Representation of Heartburn in Nonerosive Reflux Disease (NERD) Patients https://ClinicalTrials.gov/show/NCT01065649 Completed Universidade de Passo Fundo 2010-06-30
NCT01059383 Active Control, Double-blind, Double-dummy, Parallel-group, Randomized Study to Assess the Effect of VECAM 40/300, Administered at Bedtime, vs. Esomeprazole 20 mg, Administered 30-60 Min. Before Dinner, on Daytime and Nighttime GERD Symptoms https://ClinicalTrials.gov/show/NCT01059383 Completed Vecta Ltd. 2011-06-30
NCT01058564 A Prospective Evaluation of the Torax Medical Inc. Magnetic Esophageal Sphincter https://ClinicalTrials.gov/show/NCT01058564 Completed Torax Medical Incorporated 2011-10-31
NCT01058070 An Observational Clinical Feasibility Study of the Magnetic Esophageal Sphincter https://ClinicalTrials.gov/show/NCT01058070 Completed Torax Medical Incorporated 2009-07-31
NCT01057992 A Prospective Evaluation of the Torax Medical Inc. Magnetic Esophageal Sphincter https://ClinicalTrials.gov/show/NCT01057992 Completed Torax Medical Incorporated 2009-10-31
NCT01053585 Structure and Function of the Gastro-esophageal Junction https://ClinicalTrials.gov/show/NCT01053585 Completed University of Zurich 2011-05-31
NCT01050465 MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use https://ClinicalTrials.gov/show/NCT01050465 Completed University of Missouri-Columbia 2010-10-31
NCT01047800 Functional Gastrointestinal Disorder Screening Program - A Randomized Controlled Trial https://ClinicalTrials.gov/show/NCT01047800 Completed Chinese University of Hong Kong 2015-05-31
NCT01047085 Does Cholecystectomy Increase the Esophageal Alkaline Reflux? Evaluation by Impedance-pH Technique https://ClinicalTrials.gov/show/NCT01047085 Completed Istanbul University 2009-05-31
NCT01045096 Study to Evaluate the Pharmacokinetics and Safety of Dexlansoprazole in Pediatric Subjects With Symptomatic Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT01045096 Completed Takeda 2011-02-28
NCT01043185 A Study to Estimate Effect of 4 Different Doses of AZD3355 on Reflux Episodes, Which Patients With Gastroesophageal Reflux Disease (GERD) May Experience https://ClinicalTrials.gov/show/NCT01043185 Completed AstraZeneca 2010-05-31
NCT01039558 The Effect of Lansoprazole in Combination With Ecabet Sodium for Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT01039558 Completed Seoul National University Hospital 2011-03-31
NCT01027975 Comparison of Laparoscopic Nissen Versus Thal Fundoplication in Children https://ClinicalTrials.gov/show/NCT01027975 Completed Oxford University Hospitals NHS Trust NA
NCT01026103 Tri Staple Technology Stapler Used in Gastric Bypass https://ClinicalTrials.gov/show/NCT01026103 Completed Medtronic - MITG 2011-03-31
NCT01009658 MSG and Gastrointestinal Motility https://ClinicalTrials.gov/show/NCT01009658 Completed Gunma University 2015-03-31
NCT01008696 An Efficacy Study to Compare the Treatment Effects of Rabeprazole and Lansoprazole Depending on the Genotyping of CYP2C19 in Treating Reflux Esophagitis https://ClinicalTrials.gov/show/NCT01008696 Completed Janssen Korea, Ltd., Korea 2008-08-31
NCT01005251 Investigate the Effect of Different Doses of Lesogaberan (AZD3355) as add-on to PPI in GERD Patients With Partial Response to PPI https://ClinicalTrials.gov/show/NCT01005251 Completed AstraZeneca 2010-07-31
NCT00998244 Study to Evaluate the Effect of a Very Low Carbohydrate Diet on Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00998244 Completed University of North Carolina, Chapel Hill 2011-12-31
NCT00992589 Safety and Efficacy of Rabeprazole in Infants With Gastroesophageal Erosive Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00992589 Completed Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 2011-11-30
NCT00978016 A Study to Evaluate the Efficacy and Safety of Arbaclofen Placarbil (XP19986) as Adjunctive Therapy in Subjects With Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00978016 Completed Indivior Inc. 2010-12-31
NCT00926276 The Role of Anti-Reflux Surgery for Gastroesophageal Reflux Disease in Premature Infants With Bronchopulmonary Dysplasia https://ClinicalTrials.gov/show/NCT00926276 Completed The University of Texas Health Science Center, Houston 2013-05-31
NCT00911534 Comparing the Efficacy, Safety, and Tolerability of Rabeprazole ER 50 mg With Placebo in Subjects With Symptomatic Gastroesophageal Reflux Disease (sGERD) https://ClinicalTrials.gov/show/NCT00911534 Completed Eisai Inc. 2009-07-31
NCT00872755 Nissen and Gastroplasty in Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00872755 Completed G. Hatzikosta General Hospital 2008-04-30
NCT00868296 Open Label Safety Study of Enteric-Coated Spheroid Suspension in Infants Aged Less Than 12 Months With Presumed Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00868296 Completed Wyeth is now a wholly owned subsidiary of Pfizer 2008-03-31
NCT00864396 Twice Daily Prevacid for the Treatment of Laryngopharyngeal Reflux https://ClinicalTrials.gov/show/NCT00864396 Completed University of California, Davis 2008-05-31
NCT00858858 Clinical Studies on Bile Acids in Barrett’s Esophagus https://ClinicalTrials.gov/show/NCT00858858 Completed VA Office of Research and Development 2013-03-31
NCT00855361 A Pharmacokinetics, Pharmacodynamics and Safety Study of Rabeprazole in New Born Infants With Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00855361 Completed Janssen Research & Development, LLC 2011-12-31
NCT00852098 Laparoscopic Nissen Fundoplication Comparing Division Versus Non-Division of Short Gastric Vessels https://ClinicalTrials.gov/show/NCT00852098 Completed Federal University of São Paulo 2000-01-31
NCT00847808 Efficacy of Dexlansoprazole MR on Heartburn Control in Participants Previously Receiving Twice Daily Proton Pump Inhibitor Therapy https://ClinicalTrials.gov/show/NCT00847808 Completed Takeda 2010-04-30
NCT00847210 Pharmacokinetic and Safety of Dexlansoprazole in Adolescents With Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00847210 Completed Takeda 2009-09-30
NCT00839306 Rabeprazole Extended Release 50 mg Versus Ranitidine 150 mg for Maintenance of Healed Erosive Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00839306 Completed Eisai Inc. 2009-08-31
NCT00838526 Rabeprazole Extended-Release 50 mg vs. Ranitidine 150 mg for Maintenance of Healed Erosive Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00838526 Completed Eisai Inc. 2009-07-31
NCT04433507 Antireflux Efficacy of Hiatal Hernia Repairs in Sleeve Gastrectomy Patients https://ClinicalTrials.gov/show/NCT04433507 Recruiting Hopital du Sacre-Coeur de Montreal 2021-09-01
NCT00838396 A Study to Evaluate the Efficacy and Safety of Controlled Release Arbaclofen Placarbil (XP19986) in Patients With Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00838396 Completed Indivior Inc. 2006-08-31
NCT00815334 Efficacy of Endoscopic Subureteral Injection for Vesicoureteral Reflux in Adults With Decreased Bladder Compliance https://ClinicalTrials.gov/show/NCT00815334 Completed Samsung Medical Center 2008-12-31
NCT00810485 ADX10059 as an add-on Therapy to Proton Pump Inhibitors (PPIs) in Patients With Gastroesophageal Reflux (GERD) https://ClinicalTrials.gov/show/NCT00810485 Completed Addex Pharma S.A. 2009-12-31
NCT03561090 A Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors https://ClinicalTrials.gov/show/NCT03561090 Recruiting Ironwood Pharmaceuticals, Inc. 2021-06-30
NCT02954848 Phase 3 Study of TAK-438 10 mg in the Treatment of Non-Erosive Gastroesophageal Reflux Disease (NERD) https://ClinicalTrials.gov/show/NCT02954848 Completed Takeda 2018-02-25
NCT02710994 Pharmacodynamics and Safety of CDFR0209 https://ClinicalTrials.gov/show/NCT02710994 Completed Ajou University School of Medicine 2014-08-31
NCT02579460 Reflux-Induced Oxidative Stress in Barrett’s Esophagus: Response, Repair, and Epithelial-Mesenchymal-Transition https://ClinicalTrials.gov/show/NCT02579460 Enrolling by invitation Dallas VA Medical Center 2021-10-31
NCT01570842 Anthropometry in Gastroesophageal Reflux Disease and Esophageal Injury https://ClinicalTrials.gov/show/NCT01570842 Completed Mayo Clinic 2012-11-30
NCT04252144 Study of Dietary Patterns and Food Diversity in Russian GERD Patients https://ClinicalTrials.gov/show/NCT04252144 Recruiting Russian Academy of Medical Sciences 2022-09-30
NCT00787891 A Study of the Safety and Effectiveness of Rabeprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Pediatric Patients https://ClinicalTrials.gov/show/NCT00787891 Completed Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 2011-01-31
NCT00786695 Study Using Esomeprazole as a Diagnostic Test for GERD in Patients With NCCP https://ClinicalTrials.gov/show/NCT00786695 Completed National University Hospital, Singapore 2009-12-31
NCT00776997 LINX Reflux Management System Clinical Study Protocol https://ClinicalTrials.gov/show/NCT00776997 Completed Torax Medical Incorporated 2010-12-31
NCT00770913 Double-blind Comparative Study of E3810 Tablets (10 or 20 mg b.i.d.) to Evaluate Efficacy and Safety in Patients With Refractory Reflux Esophagitis https://ClinicalTrials.gov/show/NCT00770913 Completed Eisai Inc. 2009-11-30
NCT00747695 A Pharmacokinetic and Safety Study of Single and Multiple Doses of Rabreprazole in Pediatric Patients With Gastroesophageal Reflux Disease (GERD) 1 to 11 Years Old, Inclusive https://ClinicalTrials.gov/show/NCT00747695 Completed Johnson & Johnson Pharmaceutical Research & Development, L.L.C. NA
NCT00747526 A Study of Single and Multiple Doses of Rabeprazole in Pediatric Patients With Gastroesophageal Reflux Disease (GERD) 1 to 11 Months Old, Inclusive https://ClinicalTrials.gov/show/NCT00747526 Completed Janssen Research & Development, LLC 2012-02-29
NCT00744419 Intravenous (IV) Pantoprazole for Gastroesophageal Reflux Disease (GERD) in Neonates and Infants https://ClinicalTrials.gov/show/NCT00744419 Completed University of Louisville 2012-04-30
NCT00734747 Safety and Efficacy the Medigus SRS Endoscopic Stapling System in Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00734747 Completed Medigus Ltd 2011-05-31
NCT00734097 A Study of Nexium (Esomeprazole) 40 mg Once Daily in Subjects With Symptoms of Gastroesophageal Reflux Disease (GORD) After Treatment With a Full Dose of Proton Pump Inhibitor (PPI) https://ClinicalTrials.gov/show/NCT00734097 Completed AstraZeneca 2008-10-31
NCT00729339 Role of Mosapride in Patients With Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00729339 Completed Lotung Poh-Ai Hospital 2009-04-30
NCT00728481 The Role Of Gastroesophageal Reflux Disease (GERD) in Eosinophilic Esophagitis https://ClinicalTrials.gov/show/NCT00728481 Completed Mayo Clinic 2010-12-31
NCT00703534 Validation of Patient-reported Outcomes Measures for the Assessment of Gastroesophageal Reflux Disease (GERD) Symptoms https://ClinicalTrials.gov/show/NCT00703534 Completed AstraZeneca 2009-01-31
NCT00688402 Study to Compare Different Formulations of AZD3355 https://ClinicalTrials.gov/show/NCT00688402 Completed AstraZeneca 2008-06-30
NCT00687245 Pharmacokinetic Study of Esomeprazole Magnesium in Patients 1 to 11 Years-Old With Endoscopically-Proven Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00687245 Completed AstraZeneca 2008-05-31
NCT00684190 Drug Interaction Study Between AZD3355 and Nexium https://ClinicalTrials.gov/show/NCT00684190 Completed AstraZeneca 2008-06-30
NCT00674245 Effect of Pantoprazole 40mg Daily vs Placebo on Power Spectral Analysis of the Sleep EEG of Patients With GERD. https://ClinicalTrials.gov/show/NCT00674245 Completed Southern Arizona VA Health Care System 2010-07-31
NCT00660660 Local Phase IV, Gastroesophageal Reflux Disease (GERD) Sleep Study US https://ClinicalTrials.gov/show/NCT00660660 Completed AstraZeneca 2008-07-31
NCT00658775 Rabeprazole Extended-Release, 50 mg, Versus Esomeprazole, 40 mg, for Healing and Symptomatic Relief of Moderate to Severe Erosive Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00658775 Completed Eisai Inc. 2009-09-30
NCT00658632 Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Mild to Moderate Erosive Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00658632 Completed Eisai Inc. 2009-04-30
NCT00658528 Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Moderate to Severe Erosive Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00658528 Completed Eisai Inc. 2009-09-30
NCT00641264 Quality of Life Validation in Laryngitis https://ClinicalTrials.gov/show/NCT00641264 Completed AstraZeneca 2003-06-30
NCT00637845 Study Comparing Esomeprazole Magnesium 40mg Once Daily Versus Lansoprazole 30 mg Twice Daily in Symptom Control of Subjects With Persistent Gastrooesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00637845 Completed AstraZeneca 2003-02-28
NCT00635414 Open, Randomized, Two Way Crossover 40mg, Orally and Intravenously https://ClinicalTrials.gov/show/NCT00635414 Completed AstraZeneca 2002-10-31
NCT00634608 Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow https://ClinicalTrials.gov/show/NCT00634608 Completed University of Missouri-Columbia 2009-03-31
NCT00634114 Reflux Esophagitis Phase III Study (Maintenance Treatment) https://ClinicalTrials.gov/show/NCT00634114 Completed AstraZeneca NA
NCT00633932 Reflux Esophagitis Phase III Study (Initial Treatment) https://ClinicalTrials.gov/show/NCT00633932 Completed AstraZeneca NA
NCT00629564 An Open, Randomized, Two Way Crossover Study Comparing the Effect of 20mg Esomeprazole Administered Orally and Intravenously as a 15 Minute Infusion on Basal and Pentagastrin-Stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00629564 Completed AstraZeneca 2002-10-31
NCT00628342 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg qd and 40 mg qd to Placebo qd in Patients With Heartburn and Sleep Disturbances Associated With Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00628342 Completed AstraZeneca 2003-08-31
NCT00627016 A Study of Dexlansoprazole Modified Release Formulation to Treat Night Heartburn https://ClinicalTrials.gov/show/NCT00627016 Completed Takeda 2009-03-31
NCT00626535 A Multicenter, Randomized, Double-Blind Parallel-Group, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg Once Daily to Placebo qd for the Resolution of Upper Abdominal Pain in Patients With Symptomatic Gastroesophageal Reflux Disease (sGERD) https://ClinicalTrials.gov/show/NCT00626535 Completed AstraZeneca 2004-02-29
NCT00626262 Open, Randomized, Two Way Crossover Study Comparing the Effect of Esomeprazole Adminstered Orally and iv https://ClinicalTrials.gov/show/NCT00626262 Completed AstraZeneca 2002-10-31
NCT00625495 Study Comparing the Effects of Esomeprazole Adminstered Orally and Intravenously on Basal and Pentrigastrin-stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00625495 Completed AstraZeneca 2002-11-30
NCT00618150 Patient Education in Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00618150 Completed Norwegian University of Science and Technology 1999-12-31
NCT00587522 Study of the NDO Endoscopic Plication System For the Treatment of Symptomatic Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00587522 Completed NDO Surgical, Inc. 2003-05-31
NCT00576498 Novel Imaging Techniques in Barrett’s Esophagus https://ClinicalTrials.gov/show/NCT00576498 Completed Midwest Biomedical Research Foundation 2009-05-31
NCT00574925 Study to Assess Management Strategies for the Use of Esomeprazole (Nexium) in Helicobacter Pylori Infected Patients https://ClinicalTrials.gov/show/NCT00574925 Completed University of Zurich NA
NCT00557401 An Efficacy and Safety Study of XP19986 in Subjects With Symptomatic GERD https://ClinicalTrials.gov/show/NCT00557401 Completed Indivior Inc. 2008-09-30
NCT00553449 Open Label Study Evaluating Different Dosing Regimens of Rabeprazole in Gastro-esophageal Reflux Disease (GERD) Patients With Night-time Heartburn Symptoms. https://ClinicalTrials.gov/show/NCT00553449 Completed Janssen-Ortho Inc., Canada NA
NCT00551473 Open-label Comparison of 24hr Gastric pH on Days 1, 2, 7 With Once-daily Administration of Lavoltidine 40 mg. https://ClinicalTrials.gov/show/NCT00551473 Completed GlaxoSmithKline NA
NCT00539240 Role of Pain Modulation in GERD Patients Who Failed Standard Dose PPI https://ClinicalTrials.gov/show/NCT00539240 Completed VA Office of Research and Development 2010-04-30
NCT00521703 Evaluation of Topical Lidocaine Spray as Adjuvant to Upper Gastrointestinal Endoscopy in Children https://ClinicalTrials.gov/show/NCT00521703 Completed Hospital Infantil Cândido Fontoura NA
NCT00519441 Do Patients Who Have Had Surgery for Achalasia Suffer From Reflux https://ClinicalTrials.gov/show/NCT00519441 Completed University of South Florida 2009-06-30
NCT00517114 Prospective Double-blinded Randomized Controlled Trial of 12-weeks High Dose Rabeprazole (Pariet) in the Treatment of Reflux Laryngitis in Chinese Patients https://ClinicalTrials.gov/show/NCT00517114 Completed Hospital Authority, Hong Kong NA
NCT00509392 ClosureFAST vs. Laser Ablation for the Treatment of GSV Disease: A Multicenter, Single-Blinded, Randomized Study. https://ClinicalTrials.gov/show/NCT00509392 Completed Medtronic Endovascular 2008-01-31
NCT00492622 Pharmacokinetics of Immediate-Release vs. Delayed-Release Omeprazole in Gastroparesis https://ClinicalTrials.gov/show/NCT00492622 Completed University of Louisville 2008-12-31
NCT00476398 Evaluation of Patients With Non-cardiac Chest Pain https://ClinicalTrials.gov/show/NCT00476398 Completed Brigham and Women’s Hospital 2009-06-30
NCT00472550 Esomeprazole and Gastric Emptying of Beer https://ClinicalTrials.gov/show/NCT00472550 Completed Heidelberg University NA
NCT00468559 Phase 3/Safety & Efficacy of Esomeprazole in Infants https://ClinicalTrials.gov/show/NCT00468559 Completed AstraZeneca 2008-06-30
NCT00464308 A Study to Compare the Number of Patients With Gastro-Oesophageal Reflux Disease (GORD) Achieving Heartburn and Regurgitation Symptom Resolution After Treatment With Either Rabeprazole Sodium 20mg, Esomeprazole 20mg or Esomeprazole 40mg https://ClinicalTrials.gov/show/NCT00464308 Completed Janssen-Cilag Pty Ltd 2008-05-31
NCT00444275 Nexium (Esomeprazole) in Symptom Adapted Therapy in GERD Patients https://ClinicalTrials.gov/show/NCT00444275 Completed AstraZeneca 2008-10-31
NCT00444145 Do Laryngeal Tissue Changes in Patients Suspected of Having Laryngopharyngeal Reflux Predict Response to Treatment? https://ClinicalTrials.gov/show/NCT00444145 Completed Vanderbilt University Medical Center 2009-03-31
NCT00427635 Efficacy and Safety of Esomeprazole Once Daily for the Treatment of GERD in Neonatal Patients https://ClinicalTrials.gov/show/NCT00427635 Completed AstraZeneca NA
NCT00414856 Effects of AFQ056 and Baclofen on Meal-Induced Gastroesophageal Reflux https://ClinicalTrials.gov/show/NCT00414856 Completed Novartis NA
NCT00410592 Evaluation of 24-Hour Intragastric pH Using Esomeprazole, Lansoprazole, and Pantoprazole in Hispanic Patients With GERD https://ClinicalTrials.gov/show/NCT00410592 Completed AstraZeneca NA
NCT00405704 Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR) https://ClinicalTrials.gov/show/NCT00405704 Completed National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2013-06-30
NCT00405119 A Study To Investigate The Effectiveness Of AH234844 (Lavoltidine) Compared With NEXIUM And Ranitidine. https://ClinicalTrials.gov/show/NCT00405119 Completed GlaxoSmithKline 2007-03-31
NCT00394472 Symptom Improvements in Gastroesophageal Reflux Disease (GERD) Patients https://ClinicalTrials.gov/show/NCT00394472 Completed AstraZeneca 2007-06-30
NCT00392002 Examine National Characteristics & Outcome Measures of GERD Patients Using the PPI Acid Suppression Symptom (PASS) Test for Response https://ClinicalTrials.gov/show/NCT00392002 Completed AstraZeneca NA
NCT00388453 Efficacy of Dx-pH Probe in Diagnosing Extra-esophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00388453 Completed Vanderbilt University Medical Center 2012-09-30
NCT00820079 ADX10059 as a Monotherapy in Patients With Gastroesophageal Reflux (GERD) https://ClinicalTrials.gov/show/NCT00820079 Completed Addex Pharma S.A. 2009-10-31
NCT00384592 PPI Sequencing Study https://ClinicalTrials.gov/show/NCT00384592 Completed AstraZeneca 2007-05-31
NCT00382850 Clinical Trial Comparing Open and Laparoscopic Nissen Fundoplication in Children https://ClinicalTrials.gov/show/NCT00382850 Completed Johns Hopkins University 2010-11-30
NCT00378898 Feasibility of Placing Bravo PH Capsule in Proximal Esophagus https://ClinicalTrials.gov/show/NCT00378898 Completed Vanderbilt University Medical Center 2009-03-31
NCT00373997 Esophageal and Laryngeal Tissue Changes in Patients Suspected of Having Laryngopharyngeal Reflux https://ClinicalTrials.gov/show/NCT00373997 Completed Vanderbilt University 2009-03-31
NCT00373334 Safety and Efficacy Study of Axid Use in Infants Suffering From Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00373334 Completed Braintree Laboratories 2008-02-29
NCT00367614 Study Evaluating Pantoprazole in Adolescents With GERD https://ClinicalTrials.gov/show/NCT00367614 Completed Wyeth is now a wholly owned subsidiary of Pfizer NA
NCT00367159 Evaluation of the Efficiency of Autologous Adipocytes Graft in Endoscopic Treatment in Vesico-Renal Reflux in Children https://ClinicalTrials.gov/show/NCT00367159 Recruiting University Hospital, Strasbourg, France 2020-08-31
NCT00365300 Study Evaluating the Efficacy and Safety of Pantoprazole in Infants With Symptomatic Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00365300 Completed Wyeth is now a wholly owned subsidiary of Pfizer 2007-11-30
NCT00362609 Study Evaluating Pantoprazole in Neonates and Preterm Infants With GERD https://ClinicalTrials.gov/show/NCT00362609 Completed Wyeth is now a wholly owned subsidiary of Pfizer 2007-12-31
NCT00354757 CYP2C19 Genetic Polymorphism on the Accuracy of Proton-Pump Inhibitor Testing https://ClinicalTrials.gov/show/NCT00354757 Completed National Taiwan University Hospital 2008-06-30
NCT00346905 Endoscopic Implantation of Enteryx for the Treatment of GERD https://ClinicalTrials.gov/show/NCT00346905 Completed Beth Israel Deaconess Medical Center 2008-02-29
NCT00343161 Symptom Adapted Therapy in GERD Patients https://ClinicalTrials.gov/show/NCT00343161 Completed AstraZeneca 2007-08-31
NCT00336219 Symptom Assessment in Adult Patients With Erosive GERD (Gastroesophageal Reflux Disease) or enGERD (Endoscopic-negative GERD) After Treatment With Pantoprazole (BY1023/M3-343) https://ClinicalTrials.gov/show/NCT00336219 Completed Takeda 2006-11-30
NCT00326027 Efficacy of Pantoprazole in Patients Older Than 18 Years Who Have Symptoms of Non-erosive Reflux or Gastroesophageal Reflux Disease (BY1023/DE-004) https://ClinicalTrials.gov/show/NCT00326027 Completed Nycomed 2007-07-31
NCT00325676 Comparison of the Classical Healing Concept With the Complete Remission Concept After Treatment With Pantoprazole in Adult Patients With Erosive GERD (Gastroesophageal Reflux Disease) (BY1023/M3-342) https://ClinicalTrials.gov/show/NCT00325676 Completed Takeda NA
NCT00324974 The Use of Lansoprazole to Treat Infants With Symptoms of Gastroesophageal Reflux https://ClinicalTrials.gov/show/NCT00324974 Completed Takeda 2007-05-31
NCT00324532 to Assess the Efficacy and Safety of the Probiotic E. Coli Strain M17 on Patients With GERD https://ClinicalTrials.gov/show/NCT00324532 Completed BioBalance Corporation NA
NCT00321984 Safety and Efficacy of Dexlansoprazole Modified Release Formulation to Treat Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00321984 Completed Takeda 2006-12-31
NCT00312806 Effect of Pantoprazole on the Symptoms of Acid Reflux Disease in Adult Patients (BY1023/M3-341) https://ClinicalTrials.gov/show/NCT00312806 Completed Takeda 2007-03-31
NCT00307944 Study of Pantoprazole for Sleepiness Associated With Acid Reflux and Sleep Apnea https://ClinicalTrials.gov/show/NCT00307944 Completed University of Cincinnati NA
NCT00304421 Comparison of the Nighttime Effects of Two Different Drugs on Subjects With GERD https://ClinicalTrials.gov/show/NCT00304421 Completed VA Greater Los Angeles Healthcare System NA
NCT00300755 Study Evaluating Pantoprazole in Children With Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00300755 Completed Wyeth is now a wholly owned subsidiary of Pfizer 2008-04-30
NCT00295685 Nexium 40mg Once Daily vs Prevacid 30mg Twice a Day for Control of Severe GERD https://ClinicalTrials.gov/show/NCT00295685 Completed Digestive & Liver Disease Specialists NA
NCT00291746 Validation of RDQ Questionnaire https://ClinicalTrials.gov/show/NCT00291746 Completed AstraZeneca NA
NCT00287612 Necessity of Esophageal Dissection During Laparoscopic Fundoplication https://ClinicalTrials.gov/show/NCT00287612 Completed Children’s Mercy Hospital Kansas City 2009-08-31
NCT00287391 Sleep Disorders and Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00287391 Completed University of North Carolina, Chapel Hill NA
NCT00284908 Dose-Effect of S-Tenatoprazole-Na(STU-Na) 30 mg, 60 mg, 90 mg and 120 mg in Healthy Volunteers https://ClinicalTrials.gov/show/NCT00284908 Completed STEBA France 2006-11-30
NCT00272701 Esomeprazole in PPI Failures - IMPROVE https://ClinicalTrials.gov/show/NCT00272701 Completed AstraZeneca NA
NCT00261339 Determination of a Questionnaire After Treatment With Pantoprazole at Full Dose and Half Dose in Adult Patients With Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/UK-506) https://ClinicalTrials.gov/show/NCT00261339 Completed Takeda NA
NCT00261300 Long-term Pantoprazole Trial in Patients With Symptoms of Chronic Acid Peptic Complaints (BY1023/VMG-708) https://ClinicalTrials.gov/show/NCT00261300 Completed Takeda 2007-09-30
NCT00259077 Four-week Omeprazole Treatment of Non-erosive Reflux Disease in a Japanese Population https://ClinicalTrials.gov/show/NCT00259077 Completed AstraZeneca 2004-07-31
NCT00259051 A Study to Investigate the Pharmacodynamic Effect After Four-week Omeprazole Treatment of Non-erosive Reflux Disease in a Japanese Population https://ClinicalTrials.gov/show/NCT00259051 Completed AstraZeneca 2004-08-31
NCT00259012 Study Evaluating Pantoprazole Sodium Enteric-Coated Spheroid Suspension In Infants With Presumed GERD https://ClinicalTrials.gov/show/NCT00259012 Completed Wyeth is now a wholly owned subsidiary of Pfizer 2008-03-31
NCT00255190 Safety and Quality of Life Study of Dexlansoprazole Modified Release Formulation to Treat Heartburn https://ClinicalTrials.gov/show/NCT00255190 Completed Takeda 2008-06-30
NCT00251966 ASTERIX: Low Dose ASA and Nexium https://ClinicalTrials.gov/show/NCT00251966 Completed AstraZeneca NA
NCT00251927 Esomeprazole (NEXIUM) vs. Surgery https://ClinicalTrials.gov/show/NCT00251927 Completed AstraZeneca 2009-04-30
NCT00251901 Chest Pain Pilot Study https://ClinicalTrials.gov/show/NCT00251901 Completed AstraZeneca 2005-07-31
NCT00251758 Safety and Efficacy of Dexlansoprazole Modified Release Formulation to Treat Heartburn https://ClinicalTrials.gov/show/NCT00251758 Completed Takeda 2006-05-31
NCT00251745 Efficacy and Safety of Dexlansoprazole Modified Release Formulation to Treat Heartburn https://ClinicalTrials.gov/show/NCT00251745 Completed Takeda 2006-05-31
NCT00251732 Role of Pain Modulation in GERD Patients Who Failed Standard Dose Proton Pump Inhibitors (PPI) https://ClinicalTrials.gov/show/NCT00251732 Completed Southern Arizona VA Health Care System 2010-05-31
NCT00246909 Determination of the Minimal Clinically Important Difference After Treatment With Pantoprazole in Patients With Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/M3-340) https://ClinicalTrials.gov/show/NCT00246909 Completed Takeda 2006-11-30
NCT00243724 HEARD (Long Term) Study - Histology of the Esophagus in Acid-Related Disease https://ClinicalTrials.gov/show/NCT00243724 Completed AstraZeneca 2007-06-30
NCT00242736 An Open-Label Study of Once-Daily Oral Administration of Esomeprazole 40 mg in Patients With Symptoms of Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00242736 Completed AstraZeneca NA
NCT00241501 Safety of Daily Dose Esomeprazole for GERD for Pediatric and Adolescent Patients https://ClinicalTrials.gov/show/NCT00241501 Completed AstraZeneca NA
NCT00237367 A Study of Rabeprazole and Pantoprazole on Stomach Acid and Esophageal Acid Exposure in Patients With Gastroesophageal Reflux Disease (GERD) and a History of Nighttime Heartburn https://ClinicalTrials.gov/show/NCT00237367 Completed PriCara, Unit of Ortho-McNeil, Inc. NA
NCT00236392 A Study of Efficacy and Safety of “On-demand” Maintenance Therapy With Rabeprazole in Patients With Non-erosive Reflux Disease (NERD) https://ClinicalTrials.gov/show/NCT00236392 Completed Janssen Pharmaceutica N.V., Belgium NA
NCT00235677 Treatment Of Gastroesophageal Reflux Disease By Endoscopic Fundoplication, A Placebo-Controlled Study https://ClinicalTrials.gov/show/NCT00235677 Completed UMC Utrecht NA
NCT00234117 Improvement in Bronchial Asthma in Patients With Extraesophageal Reflux After Acid Suppression https://ClinicalTrials.gov/show/NCT00234117 Completed Ponce Gastroenterology Research NA
NCT00231543 Laparoscopy in Children: Does it Decrease the Metabolic, Endocrine and Inflammatory Stress Response to Surgery https://ClinicalTrials.gov/show/NCT00231543 Completed Institute of Child Health NA
NCT00229424 Verification Study on Lafutidine in Mild Reflux Oesophagitis - Double Blind Controlled Study With Famotidine - https://ClinicalTrials.gov/show/NCT00229424 Completed Taiho Pharmaceutical Co., Ltd. 2006-10-31
NCT00228527 Esomeprazole for Treatment of GERD in Pediatric Patients https://ClinicalTrials.gov/show/NCT00228527 Completed AstraZeneca NA
NCT00226044 Rectal and Oral Omeprazole Treatment of Reflux Disease in Infants. https://ClinicalTrials.gov/show/NCT00226044 Completed Rijnstate Hospital 2016-09-30
NCT00222170 Rabeprazole in Subjects With Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00222170 Completed University of Kansas Medical Center NA
NCT00220818 A Study to Evaluate the Effect of Lansoprazole on Infants With Gastroesophageal Reflux Disease. https://ClinicalTrials.gov/show/NCT00220818 Completed Takeda 2005-07-31
NCT00217347 Evaluation of Efficiency of Esophageal Capsule Endoscopy in the Screening of Patients With Gastroesophageal Reflux Disease or Dyspepsia as Compared to Upper Endoscopy https://ClinicalTrials.gov/show/NCT00217347 Completed Nantes University Hospital NA
NCT00216489 A Study of the Safety of Rabeprazole Administered to Adults With Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00216489 Completed Janssen Cilag Pharmaceutica S.A.C.I., Greece NA
NCT00215787 Investigation of the Association Between Nasal Polyposis and Extraesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00215787 Completed Head and Neck Surgery Associates 2008-09-30
NCT00214552 Evaluate the Effects on Asthma Control of Rabeprazole Given Twice Daily in Subjects With Asthma. https://ClinicalTrials.gov/show/NCT00214552 Completed Associated Scientists to Help Minimize Allergies 2005-03-31
NCT00206180 NEXIUM® in the Treatment of Moderate and Severe Erosive Esophagitis https://ClinicalTrials.gov/show/NCT00206180 Completed AstraZeneca NA
NCT00204698 Laryngopharyngeal Reflux and Proton Pump Inhibitor (PPI) Treatment https://ClinicalTrials.gov/show/NCT00204698 Completed University of Utah 2006-05-31
NCT00200642 Evaluation of the Efficiency of Radiofrequency in the Treatment of Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00200642 Completed Nantes University Hospital NA
NCT00195208 Study Comparing a Pantoprazole Formulation to the Currently Marketed Tablet for GERD and Erosive Esophagitis https://ClinicalTrials.gov/show/NCT00195208 Completed Wyeth is now a wholly owned subsidiary of Pfizer 2005-11-30
NCT00194376 Evaluation of Gastroesophageal Reflux in Patients on Continuous Positive Airway Pressure Ventilation for Obstructive Sleep Apnea https://ClinicalTrials.gov/show/NCT00194376 Completed University of Pennsylvania 2006-09-30
NCT00184522 On Demand Treatment of Reflux Disease https://ClinicalTrials.gov/show/NCT00184522 Completed Norwegian University of Science and Technology 2004-11-30
NCT00182260 A Randomized Controlled Trial of Laparoscopic Nissen Fundoplication Treatment of Patients With Chronic GERD https://ClinicalTrials.gov/show/NCT00182260 Completed McMaster University 2010-04-30
NCT00174928 A Study to Evaluate the Effect of Lansoprazole on Hospitalized Neonates With Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00174928 Completed Takeda 2005-08-31
NCT00171483 Assessment of the Role of Tegaserod Therapy in the Management of Gastroesophageal Reflux Disease (GERD) Symptoms in Patients With Incomplete Response to Proton Pump Inhibitors (PPIs). https://ClinicalTrials.gov/show/NCT00171483 Completed Novartis NA
NCT00171418 Assessment of the Effects of Tegaserod in the Management of Gastroesophageal Reflux Disease (GERD) in Patients With Incomplete Response to Proton Pump Inhibitors (PPIs). https://ClinicalTrials.gov/show/NCT00171418 Completed Novartis NA
NCT00170001 Which Supraesophageal Reflux Symptoms Reliably Respond to Proton-Pump-Inhibitor (PPI) Therapy https://ClinicalTrials.gov/show/NCT00170001 Completed Mayo Clinic 2006-08-31
NCT00165841 Maintenance Intermittent Therapy for Symptomatic GERD Patients https://ClinicalTrials.gov/show/NCT00165841 Completed Eisai Inc. 2005-12-31
NCT00165672 A Study of E3810 With Pre- and Post-Treatment pH Monitoring in Patients With Non-Erosive Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00165672 Completed Eisai Inc. 2005-10-31
NCT00165646 A Comparative Study on the Efficacy and Safety of E3810 in Patients With Non-erosive Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00165646 Completed Eisai Inc. 2005-10-31
NCT00164840 Symptomatic Gastroesophageal Reflux Disease: Double Blind Randomized Controlled Study of On-demand Therapy Versus Maintenance Therapy https://ClinicalTrials.gov/show/NCT00164840 Completed Chinese University of Hong Kong 2008-11-30
NCT00163306 Efficacy of Pantoprazole in Patients Older Than 18 Years Who Have Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/M3-339) https://ClinicalTrials.gov/show/NCT00163306 Completed Takeda NA
NCT00149851 A Study to Assess the Efficacy, Safety and Tolerability of Tegaserod Alone and in Combination With Omeprazole Given Orally in Patients With Symptoms of Symptomatic Gastroesophageal Reflux Disease (sGERD) https://ClinicalTrials.gov/show/NCT00149851 Completed Novartis 2005-06-30
NCT00141960 Famotidine in Subjects With Non-erosive Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00141960 Completed Astellas Pharma Inc NA
NCT00141817 Study Evaluating Pantoprazole in Children With GERD https://ClinicalTrials.gov/show/NCT00141817 Completed Wyeth is now a wholly owned subsidiary of Pfizer 2007-11-30
NCT00132496 Treatment of Gastroesophageal Reflux Disease in 12-16 Year Old Patients With Rabeprazole https://ClinicalTrials.gov/show/NCT00132496 Completed Eisai Inc. 2006-05-31
NCT00131248 Medical Treatment for Gastroesophageal Reflux Disease (GERD) in Preterm Infants https://ClinicalTrials.gov/show/NCT00131248 Completed The University of Texas Health Science Center, Houston 2008-03-31
NCT00057174 Economic Impact of Guidelines for Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00057174 Completed VA Office of Research and Development NA
NCT00818870 Effect of Vecam 40/300 and Vecam 20/300 Compared to Omeprazole 20 mg on Gastric pH https://ClinicalTrials.gov/show/NCT00818870 Completed Vecta Ltd. 2009-06-30

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03407456 Correlations Between Wireless pH Monitoring and Variation in Reflux Symptom Questionnaire, 7 Day Recall https://ClinicalTrials.gov/show/NCT03407456 Completed Guy’s and St Thomas’ NHS Foundation Trust 2019-08-19
NCT03390634 Physiological Predictors of Clinical Outcomes After Anti-reflux Surgery https://ClinicalTrials.gov/show/NCT03390634 Completed Guy’s and St Thomas’ NHS Foundation Trust 2019-08-19
NCT03375060 Histology Post-Endoscopic Eradication Therapy (EET) https://ClinicalTrials.gov/show/NCT03375060 Completed Northwestern University 2017-11-05
NCT03824548 Outcomes for Patients With Gastro-Esophageal Reflux Disease https://ClinicalTrials.gov/show/NCT03824548 Recruiting Tianjin Happy Life Technology Co., Ltd. 2019-05-01
NCT03214952 Drug Use Surveillance of Vonoprazan for “Gastric Ulcer, Duodenal Ulcer, and Reflux Esophagitis” https://ClinicalTrials.gov/show/NCT03214952 Completed Takeda 2018-10-31
NCT03103789 Assessment of Esophageal Epithelium Integrity With Use of a Novel Mucosal Impedance Device https://ClinicalTrials.gov/show/NCT03103789 Enrolling by invitation Vanderbilt University Medical Center 2022-08-31
NCT03077906 Study of Gastro-oesophageal Reflux in Patients Having Had Bariatric Surgery https://ClinicalTrials.gov/show/NCT03077906 Completed Brugmann University Hospital 2017-06-01
NCT03053609 Gastroesophageal Reflux and Cardiorespiratory Problems https://ClinicalTrials.gov/show/NCT03053609 Completed University of Turin, Italy 2016-12-31
NCT03020550 Correlates of GERD Symptom Severity https://ClinicalTrials.gov/show/NCT03020550 Completed Massachusetts General Hospital 2019-05-03
NCT03014453 GER Poses a Potential Risk for Late Complications of BPD https://ClinicalTrials.gov/show/NCT03014453 Completed Shengjing Hospital 2018-06-30
NCT03005080 Pharmacogenetic Testing in Children With Persistent Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT03005080 Completed Mayo Clinic 2017-12-31
NCT02959424 NEQOL Survey Spanish Validation in a Hispanic Clinic Based Population https://ClinicalTrials.gov/show/NCT02959424 Completed Instituto Ecuatoriano de Enfermedades Digestivas 2017-10-31
NCT02888808 Relationship of Obesity With GERD Among Nigerians https://ClinicalTrials.gov/show/NCT02888808 Completed Obafemi Awolowo University Teaching Hospital 2015-12-31
NCT02837627 Effect of Tube Feeding on Gastroesophageal Reflux in Preterm Infants https://ClinicalTrials.gov/show/NCT02837627 Enrolling by invitation Azienda Ospedaliera Universitaria di Bologna Policlinico S. Orsola Malpighi 2021-04-30
NCT02797756 Impact of Gastroesophageal Reflux and Aspiration on Airway Inflammation and Microbiome in Children With Chronic Cough https://ClinicalTrials.gov/show/NCT02797756 Completed NYU Langone Health 2018-12-12
NCT02708303 Mayo Clinic Foregut Surgery Report Card Questionnaire https://ClinicalTrials.gov/show/NCT02708303 Active, not recruiting Mayo Clinic 2021-03-31
NCT02629081 Image-Enhanced Endoscopy (IEE) for Diagnosis of Non-Erosive Reflux Disease https://ClinicalTrials.gov/show/NCT02629081 Completed Yale University 2016-06-30
NCT02606851 Proton Pump Inhibitor Empirical Treatment in Management of Outpatients With Gastroesophageal Reflux Disease. https://ClinicalTrials.gov/show/NCT02606851 Completed AstraZeneca 2016-12-28
NCT02575287 Minimal Injuries From Esophagus Detected by Optical Enhancement Systemâ„¢ Associated to Optical Magnification HD Scopes https://ClinicalTrials.gov/show/NCT02575287 Completed Instituto Ecuatoriano de Enfermedades Digestivas 2016-01-31
NCT02555852 Proton Pump Inhibitors and Risk of Community-acquired Pneumonia https://ClinicalTrials.gov/show/NCT02555852 Completed Canadian Network for Observational Drug Effect Studies, CNODES 2012-02-29
NCT02506634 The Primary Symptoms of GERD(Gastroesophageal Reflux Disease) in Chinese Outpatients in Gastroenterology Department https://ClinicalTrials.gov/show/NCT02506634 Completed First Affiliated Hospital, Sun Yat-Sen University 2019-01-31
NCT02495051 Esophageal Atresia: Metaplasia, Barrett https://ClinicalTrials.gov/show/NCT02495051 Completed University Hospital, Lille 2013-03-31
NCT02477475 Nexium Capsules S-CEI for Justification of Esomeprazole in Acid Related Disease for Reflux Symptom Healing Based on Patient Clinical Outcomes https://ClinicalTrials.gov/show/NCT02477475 Completed AstraZeneca 2017-02-20
NCT02457104 The Effect of PPI Therapy on Weight, Gut Microbiome, and Expression of GPR41 and GPR43 https://ClinicalTrials.gov/show/NCT02457104 Recruiting University of Colorado, Denver 2020-10-31
NCT02456779 Validation of a Non-invasive In-vitro Diagnostic Test (Peptest) Against Other Diagnostic Methods for GERD https://ClinicalTrials.gov/show/NCT02456779 Completed MAAB (Shanghai) Medical Device Limited 2017-01-31
NCT02437682 Translation and Validation of the PASS Test for GERD Patients With Partial Response to PPI: PASS-HK https://ClinicalTrials.gov/show/NCT02437682 Recruiting Chinese University of Hong Kong 2019-12-31
NCT02425553 Effects of Diet on Reflux and Dyspepsia https://ClinicalTrials.gov/show/NCT02425553 Completed University of Zurich 2015-04-30
NCT02320981 Mucosal Impedance in Pediatric Population https://ClinicalTrials.gov/show/NCT02320981 Completed Vanderbilt University Medical Center 2016-09-30
NCT02167984 Esophageal Bolus Transit in Newborns With Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT02167984 Completed University of Turin, Italy 2013-03-31
NCT02087345 Gastro-oesophageal Reflux in Oligosymptomatic Patients With Dental Erosion https://ClinicalTrials.gov/show/NCT02087345 Recruiting Brain-Gut Research Group 2020-12-31
NCT01306799 To Learn How Bone Structure and Bone Mass Change After Long-term PPI Use https://ClinicalTrials.gov/show/NCT01306799 Completed University of Pennsylvania 2015-04-30
NCT01297673 Reflux in Spinal Cord Injury Patients With Neurogenic Lower Urinary Tract Dysfunction https://ClinicalTrials.gov/show/NCT01297673 Completed Balgrist University Hospital 2010-08-31
NCT01286155 Epidemiology of Barrett’s Esophagus: A Population Based Study https://ClinicalTrials.gov/show/NCT01286155 Completed Mayo Clinic 2011-06-30
NCT02023216 Effects of Non-Nutritive Sucking on Gastroesophageal Reflux and Related Apneas in Symptomatic Preterm Infants https://ClinicalTrials.gov/show/NCT02023216 Completed Azienda Ospedaliera Universitaria di Bologna Policlinico S. Orsola Malpighi 2015-08-31
NCT02048449 Inter-rater Reliability of the Reflux Finding Score Among Gastroenterologists https://ClinicalTrials.gov/show/NCT02048449 Completed Chuncheon Sacred Heart Hospital 2014-03-31
NCT02012894 Laparoscopic Sleeve Gastrectomy and Gastroesophageal Acid Reflux https://ClinicalTrials.gov/show/NCT02012894 Completed University of Turin, Italy 2011-09-30
NCT01990339 Lansoprazole Tablets Special Drug Use Surveillance Gastroesophageal Reflux Disease With Dyspepsia Symptoms https://ClinicalTrials.gov/show/NCT01990339 Completed Takeda 2010-12-31
NCT01940185 A Post-Approval Study of the LINX® Reflux Management System https://ClinicalTrials.gov/show/NCT01940185 Active, not recruiting Torax Medical Incorporated 2020-10-31
NCT01926353 Polyacrylate Polyalcohol Copolymer for Vesicoureteral Reflux https://ClinicalTrials.gov/show/NCT01926353 Completed St. Luke’s Medical Center, Philippines 2014-02-28
NCT01867931 Epithelial Damage in GERD https://ClinicalTrials.gov/show/NCT01867931 Completed Maastricht University Medical Center 2014-05-31
NCT01865825 Proton Pump Inhibitor (PPI) Responsive Eosinophilic Esophagitis EoE: Gastroesophageal Reflux Disease (GERD) or Eosinophilic Esophagitis (EoE)? https://ClinicalTrials.gov/show/NCT01865825 Completed Mayo Clinic 2016-12-31
NCT01797939 Predictors of Proton Pump Inhibitor Response in Gastroesophageal Reflux Disease Patients https://ClinicalTrials.gov/show/NCT01797939 Completed Seoul National University Bundang Hospital 2012-12-31
NCT01777867 Cough Reflex Sensitivity and Bronchial Hyper-responsiveness https://ClinicalTrials.gov/show/NCT01777867 Completed Mayo Clinic 2016-02-29
NCT01776827 Long-term Outcome of Laparoscopic Hiatal Hernia Repair With or Without Alloderm Mesh at a University Hospital https://ClinicalTrials.gov/show/NCT01776827 Completed University of Nebraska 2014-06-30
NCT01742377 Minimal Change Esophagitis by i-Scan Endoscopy in Dyspeptic Patients https://ClinicalTrials.gov/show/NCT01742377 Completed Prince of Songkla University 2014-07-31
NCT01741441 Laparoscopic Total Fundoplication for Duodenogastroesophageal Reflux https://ClinicalTrials.gov/show/NCT01741441 Completed University of Turin, Italy 2007-06-30
NCT01667042 Scleroderma Lung: Role of Gastroesophageal Reflux, Microaspiration and Cough https://ClinicalTrials.gov/show/NCT01667042 Completed Mayo Clinic 2014-06-30
NCT01635959 Prevalence of Gastroesophageal Reflux Disease (GERD) in Patients With Upper Gastrointestinal Tract Symptoms in Egypt https://ClinicalTrials.gov/show/NCT01635959 Completed AstraZeneca 2014-07-31
NCT01606449 Follow-up of Patients Operated Upon for Type II-IV Hiatal Hernia https://ClinicalTrials.gov/show/NCT01606449 Completed University of Bologna 2011-12-31
NCT01601379 Observational Study (This Means That no Drug is Tested) in Patients Suffering of Gastroesophageal Reflux Disease. https://ClinicalTrials.gov/show/NCT01601379 Completed Janssen-Cilag International NV 2011-06-30
NCT01576289 Analysis of Biopsies From the Upper Gastrointestinal Tract https://ClinicalTrials.gov/show/NCT01576289 Completed Medical University of Graz 2012-05-31
NCT01560910 Detection of Minimal Change Esophagitis by I-scan https://ClinicalTrials.gov/show/NCT01560910 Completed Maharaj Nakorn Chiang Mai Hospital 2010-12-31
NCT01536457 Reflux Disease Therapy in the Management of Childhood Asthma-data Entry and Analysis Only https://ClinicalTrials.gov/show/NCT01536457 Completed Children’s Center for Digestive Health Care 2012-09-30
NCT01536080 Analysis of GERD Symptoms Using Gastroesophageal Reflux Impact Score Questionnaire for Quality of Life https://ClinicalTrials.gov/show/NCT01536080 Completed Seoul National University Bundang Hospital NA
NCT01507298 Physical Activity and Gastrointestinal Investigations https://ClinicalTrials.gov/show/NCT01507298 Completed Imperial College London 2013-07-31
NCT01489735 The Use of International GerdQ Questionnaire https://ClinicalTrials.gov/show/NCT01489735 Completed AstraZeneca 2012-06-30
NCT01432392 Symptom Control and Impact on Daily Life in Patients With Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT01432392 Completed AstraZeneca 2012-04-30
NCT01389401 Salivary Epidermal Growth Factor (EGF) Concentration Before and After Treatment of Reflux Laryngitis https://ClinicalTrials.gov/show/NCT01389401 Completed Faculdade de Ciências Médicas da Santa Casa de São Paulo 2011-01-31
NCT01374074 Racial Disparity in Barrett’s Esophagus https://ClinicalTrials.gov/show/NCT01374074 Completed University of North Carolina, Chapel Hill 2014-01-31
NCT01373385 Prospective Pediatric Vesicoureteral Reflux Surgery Database https://ClinicalTrials.gov/show/NCT01373385 Completed Connecticut Children’s Medical Center 2016-11-30
NCT01373125 Is the Neosquamous Epithelium “Normal” Following Endoscopic Ablation of Dysplastic Barrett’s Esophagus? https://ClinicalTrials.gov/show/NCT01373125 Completed University of North Carolina, Chapel Hill 2014-10-31
NCT01360515 A Study of Disposable Transnasal Esophagoscope https://ClinicalTrials.gov/show/NCT01360515 Completed Yonsei University 2011-02-28
NCT03347903 Prevalence and Clinical Characteristics of Patients With Jackhammer Esophagus and Symptoms of Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT03347903 Completed Medical University of Vienna 2017-05-30
NCT01321567 Quality of Life in New Treatable Therapy as Rabeprazole Option for Refractory Reflux Esophagitis https://ClinicalTrials.gov/show/NCT01321567 Completed Eisai Inc. 2013-03-01
NCT01921686 Morphological Markers of Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT01921686 Active, not recruiting Baylor College of Medicine 2014-09-30
NCT04306380 Transoral Incisionless Fundoplication Database Repository (TIF) https://ClinicalTrials.gov/show/NCT04306380 Recruiting Indiana University 2029-12-31
NCT04268719 Near Focus NBI-Driven Artificial Intelligence for the Diagnosis of Gastro-Oesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT04268719 Completed King’s College Hospital NHS Trust 2018-07-26
NCT04248296 Evaluate the Intestinal Microbiome in Patients With Erosive Gastroesophageal Reflux Disease and in Asymptomatic Healthy Controls https://ClinicalTrials.gov/show/NCT04248296 Completed University of Sao Paulo General Hospital 2019-02-20
NCT04094402 Epi-GERD Study: Epidemiological Evaluation in Patients With Gastro-Esophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT04094402 Recruiting Scandinavia Pharma 2023-12-31
NCT04034017 Gastroesophageal Reflux Disease Among College Students https://ClinicalTrials.gov/show/NCT04034017 Completed King Khalid University 2019-06-01
NCT03959020 Applying Long-term Follow-up to Improve Patient Selection in Laparoscopic Anti-reflux Surgery https://ClinicalTrials.gov/show/NCT03959020 Enrolling by invitation University of Southern Denmark 2019-05-01
NCT03848494 True Short Esophagus in Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT03848494 Completed University of Bologna 2017-12-31
NCT03835663 The Bacterial Composition of the Stomach in Reflux Disease https://ClinicalTrials.gov/show/NCT03835663 Recruiting Imperial College London 2019-06-01
NCT03735862 Complications, Outcomes and Revisions Following Hiatal Hernia Repair With MIROMESH https://ClinicalTrials.gov/show/NCT03735862 Completed Miromatrix Medical Inc. 2018-06-01
NCT03669874 Endoscopic Fundoplication With MUSE System https://ClinicalTrials.gov/show/NCT03669874 Recruiting IRCCS San Raffaele 2021-09-16
NCT03646045 Transpyloric Feeding for Prevention of Micro-aspiration https://ClinicalTrials.gov/show/NCT03646045 Recruiting Nemours Children’s Clinic 2018-12-31
NCT03596411 The Detection of Barrett’s Esophagus by Gastrointestinal Endoscopy Prevents Esophageal Carcinoma in Morbid Obese After Sleeve Gastrectomy https://ClinicalTrials.gov/show/NCT03596411 Recruiting Centre Hospitalier Universitaire de Nice 2023-05-17
NCT03562026 S-CEI of Nexium in Paediatric Patients https://ClinicalTrials.gov/show/NCT03562026 Active, not recruiting AstraZeneca 2020-12-31
NCT03418350 The Role of Laryngopharyngeal Reflux in IPF https://ClinicalTrials.gov/show/NCT03418350 Recruiting National Jewish Health 2020-12-31
NCT01262755 Temple Registry for the Investigation of African American Gastrointestinal Disease Epidemiology https://ClinicalTrials.gov/show/NCT01262755 Completed Temple University 2015-01-31
NCT01215305 A Cross-sectional Study on the Prevalence and Extraesophageal Symptoms of Gastroesophageal Reflux Disease(GERD) in Patients With Upper GI Symptoms, Visiting the Outpatient Departments of Peripheral Hospitals in Greece https://ClinicalTrials.gov/show/NCT01215305 Completed AstraZeneca 2011-03-31
NCT01204931 Can We Predict Who Has Gastroesophageal Reflux Disease (GERD)? https://ClinicalTrials.gov/show/NCT01204931 Completed Vanderbilt University 2013-07-31
NCT01200550 The Study to Describe Symptom Control and Impact on Daily Life in Gastroesophageal Reflux Disease (GERD) Patients https://ClinicalTrials.gov/show/NCT01200550 Completed AstraZeneca 2011-09-30
NCT01167543 Relationship and Pathophysiology of Gastroesophageal Reflux and Dental/Periodontal Disease https://ClinicalTrials.gov/show/NCT01167543 Completed University of California, San Francisco NA
NCT01134367 An Epidemiological Study to Describe Symptom Control and Impact of Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT01134367 Completed AstraZeneca 2010-12-31
NCT01103804 Non-interventional Study to Evaluate the Change in Symptoms Scores and Treatment Response After 4 Weeks of Proton-Pump Inhibitors (PPI) Treatment https://ClinicalTrials.gov/show/NCT01103804 Completed AstraZeneca 2010-09-30
NCT01099735 Effect of Continuous Positive Airway Pressure (CPAP) on Lower Esophageal Sphincter Pressure in Morbidly Obese Patients https://ClinicalTrials.gov/show/NCT01099735 Completed Oregon Health and Science University 2011-12-31
NCT01091805 Correlation of Oropharyngeal Pepsin and Gastroesophageal (GE) Reflux https://ClinicalTrials.gov/show/NCT01091805 Completed Wake Forest University Health Sciences 2013-09-30
NCT03871426 Manual Therapy Effects on Upper and Lower Esophageal Sphincter Pressures https://ClinicalTrials.gov/show/NCT03871426 Completed University Hospital, Motol 2019-06-13
NCT01053286 Stimulation of Sensation and Improvement in Swallowing Using Oral Capsaicin https://ClinicalTrials.gov/show/NCT01053286 Completed University of California, Davis 2012-07-31
NCT01041105 Gastric Bypass After Previous Anti-reflux Surgery https://ClinicalTrials.gov/show/NCT01041105 Completed University of California, San Francisco 2009-06-30
NCT01020890 Prevalence of Gastroesophageal Reflux Disease in Primary Care Patients With Upper Gastrointestinal Symptoms https://ClinicalTrials.gov/show/NCT01020890 Completed AstraZeneca 2010-04-30
NCT01018160 Practice and Patient Compliance on the PPI (Proton Pump Inhibitors) Treatment of Gastroesophageal Reflux in South Korea https://ClinicalTrials.gov/show/NCT01018160 Completed Janssen Korea, Ltd., Korea 2009-02-28
NCT00963144 Diagnosis and Response to Treatment Using a Reliable Gastroesophageal Reflux Disease (GERD) Questionnaire: An In Clinical Practice Study https://ClinicalTrials.gov/show/NCT00963144 Completed AstraZeneca 2009-11-30
NCT00951093 Gastroesophageal Reflux Disease (GERD) Before and After Gastric Bypass https://ClinicalTrials.gov/show/NCT00951093 Completed Clinica Gastrobese 2012-12-31
NCT00914342 Prevalence and Impact in Work Productivity of Gastroesophageal Reflux Disease (GERD) in Primary Care Patients With Upper Gastrointestinal (GI) Symptoms Using GerdQ https://ClinicalTrials.gov/show/NCT00914342 Completed AstraZeneca NA
NCT00901004 The Clinical Significance of Minimal Change in Reflux Esophagitis Based on the Gastroesophageal Reflux Disease Questionnaire https://ClinicalTrials.gov/show/NCT00901004 Completed AstraZeneca NA
NCT00890201 Pancreaticobiliary Reflux in Patients Without Cholelithiasis https://ClinicalTrials.gov/show/NCT00890201 Completed Cirujanos la Serena 2009-07-31
NCT00886197 Diagnostic Efficacy of Narrow Band Imaging in Patients With Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00886197 Completed National Taiwan University Hospital 2009-04-30
NCT00885469 PillCam® ESO 2 in Esophageal Pathologies https://ClinicalTrials.gov/show/NCT00885469 Completed Medtronic - MITG 2009-03-31
NCT00884247 Structured Treatment of Gastroesophageal Reflux in a Company Health Care Setting, -Effect on Quality of Life, Symptoms and Productivity https://ClinicalTrials.gov/show/NCT00884247 Completed AstraZeneca NA
NCT00865995 Pepsin As A Biomarker For Aspiration https://ClinicalTrials.gov/show/NCT00865995 Completed Medical College of Wisconsin 2012-12-31
NCT00842855 Partial Response to PPI Treatment: The Cost to Society and the Burden to the Patient - a Study in France https://ClinicalTrials.gov/show/NCT00842855 Completed AstraZeneca 2010-11-30
NCT00842387 Evaluation Study of a Management Strategy for Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00842387 Completed AstraZeneca NA
NCT03214081 Special Drug Use Surveillance of Vonoprazan for “Maintenance Therapy of Reflux Esophagitis: Long-term Use” https://ClinicalTrials.gov/show/NCT03214081 Completed Takeda 2018-08-31
NCT02618044 Laparoscopic Roux-en-Y Gastric Bypass and Gastro-esophageal Reflux https://ClinicalTrials.gov/show/NCT02618044 Completed University of Turin, Italy 2015-02-28
NCT00833573 National Survey on GERD Patients (Adults and Children) https://ClinicalTrials.gov/show/NCT00833573 Completed AstraZeneca NA
NCT00830115 Pantoprazole 20/40 mg in the Treatment of Symptomatic Reflux Disease With Focus on Sleep Disorders https://ClinicalTrials.gov/show/NCT00830115 Completed Nycomed 2009-05-31
NCT00829738 Efficacy of Pantoprazole 20/40 mg Once Daily (od) in Patients Older Than 12 Years Who Have Gastrointestinal Symptoms of Reflux Disease https://ClinicalTrials.gov/show/NCT00829738 Completed Nycomed 2009-04-30
NCT04085211 Image-Enhanced Endoscopy in the Gastrointestinal Tract https://ClinicalTrials.gov/show/NCT04085211 Recruiting King’s College Hospital NHS Trust 2022-02-28
NCT01406210 RESULT (REflux Surgery in Lung Transplantation) Preliminary Study Protocol https://ClinicalTrials.gov/show/NCT01406210 Completed Duke University 2013-06-30
NCT03976739 Study on the Effect of Bile Reflux on Gastric Cancer and Its Precancerous Lesions: a Cross-sectional Study. https://ClinicalTrials.gov/show/NCT03976739 Recruiting Xijing Hospital of Digestive Diseases 2019-11-30
NCT00786773 Survey to Describe Impact of Reflux Disease on Everyday Life in GERD Patients Before and After 4 Weeks Treatment. https://ClinicalTrials.gov/show/NCT00786773 Completed AstraZeneca NA
NCT00768443 Symptoms and Management Strategies in Gastroesophageal Reflux Disease (GERD) https://ClinicalTrials.gov/show/NCT00768443 Completed AstraZeneca NA
NCT00768196 Prevalence of EED and Quality of Life Evaluated by Gastroesophageal Reflux Disease (GERD)-Q in Korean GERD Patients https://ClinicalTrials.gov/show/NCT00768196 Completed AstraZeneca NA
NCT00730106 Endoscopic Findings in Patients With Typical Gastroesophageal Reflux Disease (GERD) Symptoms https://ClinicalTrials.gov/show/NCT00730106 Completed Lotung Poh-Ai Hospital 2009-07-31
NCT00698178 Waist Circumference Versus Body Mass Index to Predict Severity of Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00698178 Completed Lotung Poh-Ai Hospital 2009-07-31
NCT00697177 The Prevalence of Gastro-oesophageal Reflux in Chronic Lung Disease https://ClinicalTrials.gov/show/NCT00697177 Completed Bayside Health 2009-06-30
NCT00695838 National Survey on Gastroesophageal Reflux Disease (GERD) Patients https://ClinicalTrials.gov/show/NCT00695838 Completed AstraZeneca NA
NCT00691171 Electronic Health Record (EHR)-Based Intervention for Gastroesophageal Reflux Disease (GERD) and Chronic Non-steroidal Anti-inflammatory Drug (NSAID) Use https://ClinicalTrials.gov/show/NCT00691171 Completed AstraZeneca 2008-06-30
NCT00688675 Gastroesophageal Reflux Disease (GERD) Segmentation: Document How Swiss General Practitioners (GPs) Allocate Their GERD Patients to the Three GERD Patient Segments https://ClinicalTrials.gov/show/NCT00688675 Completed AstraZeneca 2008-08-31
NCT00681837 Prevalence of Gastroesophageal Reflux During Childhood and Teenage Years in France https://ClinicalTrials.gov/show/NCT00681837 Completed AstraZeneca NA
NCT00634023 Canadian, Multi-Centre Study of Symptom Burden and Clinical Management in Subjects With GERD https://ClinicalTrials.gov/show/NCT00634023 Completed AstraZeneca 2008-05-31
NCT00614536 Study of Changes in Reflux Symptoms and Reflux Finding Score According to Rabeprazole Treatment Period https://ClinicalTrials.gov/show/NCT00614536 Completed Janssen Korea, Ltd., Korea 2008-04-30
NCT00590239 Barrett’s Esophagus Related Neoplasia (BERN) Project https://ClinicalTrials.gov/show/NCT00590239 Recruiting Midwest Biomedical Research Foundation 2021-11-30
NCT00588939 Confocal Laser Microscopy in Non Erosive Reflux Disease https://ClinicalTrials.gov/show/NCT00588939 Completed Mayo Clinic 2012-12-31
NCT00587392 Endoscopic Full-Thickness Plication for the Treatment of GERD: Long-Term Multicenter Results https://ClinicalTrials.gov/show/NCT00587392 Completed NDO Surgical, Inc. 2007-09-30
NCT00574327 Progression of Gastroesophageal Reflux Disease and Barrett’s Esophagus and the Creation of a Barrett’s Registry https://ClinicalTrials.gov/show/NCT00574327 Recruiting Midwest Biomedical Research Foundation 2023-10-31
NCT00567619 LIFE NIS, GERD-Patients - Evaluation of Burden of Disease Determined by GERD Impact Scale (GIS) https://ClinicalTrials.gov/show/NCT00567619 Completed AstraZeneca NA
NCT00567021 German PMS Trial (AWB) to Evaluate Therapy in Reflux Disease and NSAR-Symptoms https://ClinicalTrials.gov/show/NCT00567021 Completed AstraZeneca NA
NCT00562094 Efficacy of Pantoprazole in Patients Older Than 12 Years With Reflux Associated Sleep Disorders (PULS) https://ClinicalTrials.gov/show/NCT00562094 Completed Nycomed 2009-04-30
NCT00561730 Efficacy of Pantoprazole in Patients Older Than 12 Years Who Have Symptoms of Non-Erosive Reflux Disease (NERD) or Erosive Gastroesophageal Reflux Disease (eGERD) https://ClinicalTrials.gov/show/NCT00561730 Completed Nycomed NA
NCT00545883 Impact of GERD on Daily Life (NIS) https://ClinicalTrials.gov/show/NCT00545883 Completed AstraZeneca NA
NCT00513331 Barrett’s Esophagus & Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00513331 Completed Valley Health System 2013-12-31
NCT00507377 Foreshortened Esophagus and Its Surgical Therapy https://ClinicalTrials.gov/show/NCT00507377 Completed University of Bologna 2007-07-31
NCT00482885 Coordination Versus Pressure in Oesophageal Peristalsis https://ClinicalTrials.gov/show/NCT00482885 Completed Guy’s and St Thomas’ NHS Foundation Trust 2010-08-31
NCT00481949 Assessment of Gastro-esophageal Reflux Using Endo-Flip vs Bravo https://ClinicalTrials.gov/show/NCT00481949 Completed Guy’s and St Thomas’ NHS Foundation Trust 2011-05-31
NCT00462137 The Influence of Hypnotic Medications on Sleep Arousal and Its Effect on Gastroesophageal Reflux https://ClinicalTrials.gov/show/NCT00462137 Completed Thomas Jefferson University 2008-03-31
NCT00461604 High Dosage Esomeprazole and Baclofen for Therapy of Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00461604 Completed Technische Universität München 2008-05-31
NCT00455078 GI Reflux in Lung Transplant and Its Relationship to Chronic Rejection https://ClinicalTrials.gov/show/NCT00455078 Completed University of Chicago 2010-01-31
NCT00431756 Novel Biomarkers in the Neoplastic Progression of Barrett’s Esophagus https://ClinicalTrials.gov/show/NCT00431756 Active, not recruiting Johns Hopkins University 2022-06-30
NCT00321503 Study of an Oropharyngeal Aerosolized pH Probe for Diagnosing Laryngopharyngeal Reflux (LPR) https://ClinicalTrials.gov/show/NCT00321503 Completed Emory University 2007-05-31
NCT00260572 Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT00260572 Active, not recruiting University of Pittsburgh 2050-12-31
NCT00200980 Importance of Non-Acid Reflux in Asthma in Children https://ClinicalTrials.gov/show/NCT00200980 Completed Nemours Children’s Clinic NA
NCT00165022 Development of a Novel Disease-Specific Quality of Life Questionnaire for Gastroesophageal Reflux Disease (GERD) Patients in Chinese Population https://ClinicalTrials.gov/show/NCT00165022 Completed Chinese University of Hong Kong NA
NCT00061724 Medical and Surgical Treatment of Esophageal Reflux https://ClinicalTrials.gov/show/NCT00061724 Completed National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) NA
NCT00795093 Partial Response to Proton Pump Inhibitors (PPI) Treatment: The Cost to Society and the Burden to the Patient - a Study in the US https://ClinicalTrials.gov/show/NCT00795093 Completed AstraZeneca 2010-01-31
NCT00260585 Esophageal Cancer Risk Registry https://ClinicalTrials.gov/show/NCT00260585 Recruiting University of Pittsburgh 2050-12-31

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03143608 GERD Treatment With Transoral Incisionless Fundoplication (TIF) Following Hiatal Hernia Surgery https://ClinicalTrials.gov/show/NCT03143608 Completed Mavrelis, Peter G., M.D. 2016-12-31
NCT02988934 The WATS3D (Wide Area Transepithelial Sample Biopsy With 3-Dimensional Computer-Assisted Analysis) U.S. Registry https://ClinicalTrials.gov/show/NCT02988934 Recruiting CDx Diagnostics 2026-04-30
NCT02923362 Registry of Outcomes From AntiReflux Surgery https://ClinicalTrials.gov/show/NCT02923362 Recruiting The Heartburn Foundation 2020-05-31
NCT02793479 Radiofrequency Ablation in Patients With Barrett’s Esophagus https://ClinicalTrials.gov/show/NCT02793479 Recruiting Austrian Society Of Surgical Oncology 2020-12-31
NCT02479438 Gastroesophageal Reflux Disease Prospective Registry https://ClinicalTrials.gov/show/NCT02479438 Recruiting Baylor Research Institute 2030-01-31
NCT01954667 Anthropometric Measures and Severity of Gastroesophageal Reflux Disease https://ClinicalTrials.gov/show/NCT01954667 Completed Ain Shams University 2013-08-31
NCT01776346 Barrett’s Esophagus Patient Registry https://ClinicalTrials.gov/show/NCT01776346 Recruiting Massachusetts General Hospital 2021-12-31
NCT04312633 Clinical Utility of WATS3D: A 5-Year Prospective Study https://ClinicalTrials.gov/show/NCT04312633 Recruiting CDx Diagnostics 2025-04-01
NCT03868267 Japanese Upper GI Symptoms Compared With Iranian and Canadian Patients Presenting https://ClinicalTrials.gov/show/NCT03868267 Recruiting Hamilton Health Sciences Corporation 2021-02-28
NCT03853772 The Johns Hopkins Heartburn Center Registry https://ClinicalTrials.gov/show/NCT03853772 Enrolling by invitation Johns Hopkins University 2025-12-31
NCT03661151 Comparison of Treatment Outcome and Cost-effectiveness for GERD https://ClinicalTrials.gov/show/NCT03661151 Recruiting Korea University Anam Hospital 2020-10-25
NCT03616119 Gastroesophageal Reflux Disease in Azerbaijan https://ClinicalTrials.gov/show/NCT03616119 Active, not recruiting Azerbaijan Gastroenterology and Hepatology Association 2019-08-01
NCT03524781 Treatment of Newly Diagnosed Gastroesophageal Reflux Disease in a National Population-based Cohort https://ClinicalTrials.gov/show/NCT03524781 Active, not recruiting University of Southern Denmark 2019-01-01